INFLAMMATION All information taken directly from Understanding Zoonotic Diseases by Janet Amundson Romich. Thomson Delmar publishing.

Slides:

Advertisements

Similar presentations

AVOIDANCE & TREATMENT OF INFECTIOUS DISEASE

Advertisements

The Body’s Defenses California Standards 10.a., b. & c.

4 Tissue: The Living Fabric: Part B 6/23/2012 MDufilho.

The Immune System In this lesson, you will Learn About…

The Immune Stystem.

The Immune System Small Pox A white blood cell eating bacteria.

The Immune System Non-Specific Immunity. What You Should Know The human body has the capacity to protect itself against pathogens, some toxins and cancer.

Lymphatic System and Immunity Human Anatomy and Physiology II Oklahoma City Community College Dennis Anderson.

The Immune System.

Immunology Non-specific Host Defenses Non-specific means that the defenses that are used to protect the body act the same no matter what the infection.

An Overview of the Body’s Defenses. The first line of defense, the skin and mucous membranes, prevents most microbes from entering the body.

Cellular Response Adaptive Disturbances of growth Inflammation and repair Immune response Non Adaptive Degeneration Neoplasia Dysplasia Necrosis.

Chapter 24 The Immune System

Inflammation and Repair

Inflammation Dr. Raid Jastania.

Physical and Chemical Barriers to Infection Week 12.

Lymphatic System The Body’s Defense System. Nonspecific Defense First Line of Defense –Skin –Mucous Membrane –Secretions.

Lymphatic and Immune System The Body’s Defense. Nonspecific Defense First Line of Defense –Skin –Mucous Membrane –Secretions.

Lectin: proteins that bind to a carbohydrate

ACUTE INFLAMMATION.

Immune System. Means of Defense (3 categories) First two are Nonspecific A. Barriers –Doesn’t distinguish between agents –Helps Prevent Entry into the.

Bellwork Discuss with your group what you think is happening in the following processes. Why does your body undergo an allergic reaction? Why do some.

Lecture 23 Immune System. Introduction A human or animal must defend itself against multitude of different pathogens including viruses, bacteria, fungi,

Maintaining Healthy Systems. The 10 leading causes of death (WHO, 2008) World Deaths in millions % of deaths Ischaemic heart disease % Stroke and.

The First and Second Lines of Defense Against Disease BY JEFF HOFFMAN.

Mr. Mah Living Environment Lecture 12.  Give THREE examples of vectors:  FliesTicks  MosquitoesSquirrels  RatsFleas  What are the 4 types of pathogens?

The Immune System The Body’s Lines of Defense. Intro Questions What is “disease”? What causes disease? How does our body attempt to maintain homeostasis?

Announcements Exams- Extra Credit - Lab 5 - Lymphatic System.

Blood, Sweat and Tears Also, mucus, stomach acids, skin, nasal secretions, and saliva.

Immunity Biology 2122 Chapter 21. Introduction Innate or nonspecific defense: – First-line of defense – Second-line of defense The adaptive or specific.

Introduction to pathology Inflammation lecture 1

Nonspecific Defense Against Disease Section 33.2.

Unit 4 – Immunology and Public Health Immune system.

UNIVERSITY COLLEGE OF HUMANITIES Technical Lab Analysis Department. Lectures of Histopathology. INFLAMMATION NOVEMBER –

Immune System Phagocytes Killer T-cells Macrophages

The Immune System Chapter 43 ~. PCA: List the organs involved in the immune sytem:

Major Events in the Local Inflammatory Response.

Host Defenses Overview and Nonspecific Defenses I- C Host Defenses Overview and Nonspecific Defenses I- C MIcro451 Immunology Prof. Nagwa Mohamed Aref.

(Inflammatory Response)

Immunology Antibody Antigen An antigen stimulates an immune response from a specific antibody Antibody can only take part in an immune response.

Inflammation Dr. Ahmad Hameed MBBS,DCP, M.Phil. Definition Inflammation is a protective response involving host cells, blood vessels, proteins and other.

Inflammation Chapter 12 Copyright © 2014 by Mosby, an imprint of Elsevier Inc.

TISSUE RESPONSE TO INJURY BTEC Extended Diploma in Sport (Performance and Excellence)

CHAPTER 43 THE BODY’S DEFENSES Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings Section A: Nonspecific Defenses Against Infection.

INFLAMMATION COURSE CODE : PHR 214 COURSE TEACHER : ZARA SHEIKH.

Activity…  Design an emergency plan to protect people (ex. LRHS students or people attending a concert) from an attack.  If an attack were to occur,

Unit 4 - Immunology and Public Health CfE Higher Human Biology Non-Specific Defences.

Unit 4 Immunology & Public Health

Tissue Repair Clot Clean up Scab Restored blood supply Granulation

Inflammation (1 of 5) Ali Al Khader, M.D. Faculty of Medicine

Inflammation Fatima obeidat , MD,.

مكونات المناعة Components of Immunity

Chapter 43 The Immune System.

Chapter 30 / Chapter 31 * PowerNotes Lab Infections 12

Chemical and Biological Injury

Acute inflammation 2 By Dr. S. Homathy.

Innate Immunity Fever is an abnormally high body temperature due to resetting of the hypothalamic thermostat. Non-specific response: speeds up body reactions.

TISSUE RESPONSE TO INJURY

IMMUNE/LYMPHATIC SYSTEM

Defense Against Infectious Diseases

Chapter 35 Innate Immunity.

Complement Complement proteins become activated when they encounter antigen Cascading enzyme reactions concentrate activated complement at infection site.

Presentation transcript:

INFLAMMATION All information taken directly from Understanding Zoonotic Diseases by Janet Amundson Romich. Thomson Delmar publishing

Inflammation is a reaction to any traumatic event in the body. Ex: local injury irritation microbe invasion toxin release Once the initial traumatic event has occurred, a chain reaction takes place that the site of the damaged tissue. The chain reaction includes calling beneficial cells and fluids into the injured area. Some of the earliest changes occur in the vasculature near the damaged tissue – these changes are controlled by the nervous system and the cytokines (chemical mediators) released by blood and tissue cells.

The first response to damaged tissue is vasoconstriction (narrowing of the blood vessels) – this lasts only for a few seconds or minutes and is rapidly followed by vasodilation (widening of the blood vessels). Vasodilation causes increased blood flow to the damaged area, which causes the redness and heat. Vasodilation also causes the endothelial cells lining the capillaries to stretch and form gaps through which blood components can leak into the extracellular spaces. The fluid (exudate) that escapes is typically plasma and it accumulates in the tissues causing edema (local swelling and hardness) The accumulation of fluid, cells and cell debris signals the neutrophils to the area.

After a time, phagocytes come to the damaged area. They clear the area of fluid, cellular debris, dead neutrophils and damaged tissue. Lymphocytes react by producing antibodies to kill intruders directly.

TISSUE INJURY Inflammation triggered by a traumatic event VASODILATION Following brief vasoconstriction, vasodilation causes increased blood flow to the damaged site providing delivery of plasma proteins and phagocytes INCREASED PERMEABILITY Blood components such as plasma move to the damaged site and leak from blood vessels into tissues and extracellular spaces MIGRATION OF PHAGOCYTES Neutrophils, macrophages and lymphocytes squeeze through gaps in the endothelial cells of capillaries and move to the damaged site in response to chemotactic agents released by damaged tissue PHAGOCYTOSIS Phagocytes attach to and engulf foreign particles. Foreign particles are destroyed by enzymes present in the phagocytes. Lymphocytes react in a specific manner.