Drug Investigation Assignment

 Depressant that acts on CNS  Naturally found in CNS › Protects cells from oxygen starvation  Odorless  Colorless  Nearly Tasteless  Can be liquid, pill, or powder  Can be felt within the first min

 FDA Banned GHB  GHB makers came out with GBL  Used as sleep aid & muscle enhancer  Street Names: firewater, lactone, blue nitro, vitality  FDA banned GBL too

 January 31, 2000  Controlled Substance  Schedule 1  FDA approved Schedule 4

 First synthesized  1960s- Used as anesthetic & hypnotic  1980s- Becomes available in food stores  FDA bans over-the counter- Sale  U.S. states place GHB in schedules 1-5  Becomes illegal, FDA approves Xyrem for narcolepsy

 Anesthetic  Hypnotic  Clinical Depression  Alcoholism  Narcolepsy/insomnia

 Low Dose-Moderate › Increased sex drive › Dizziness › Slow heart rate › Muscle tremors  High Dose: › Sweating › Blackouts/memory lapses › Respiratory arrest › Loss of coordination  Overdose: › Nausea/vomiting › Seizures › Amnesia › Irregular/shallow breathing

 Feelings of Euphoria  Confusion  Hallucinations  Lowered Inhibitions

GHB DoseCommon Effects 1 gram or less Relaxation similar to alcohol intoxication 1 to 2 grams Euphoria, reduced inhibitions, enhanced sensuality and sexuality, increased sensory stimulation 2 to 4 grams Speech and motor skill interference 4 or more Agitation, combativeness, confusion, loss of coordination, seizure-like posturing of the limbs, respiratory depression, urinary and fecal incontinence, vomiting, wavering states of consciousness, overdose death

 ml ml   on.htm on.htm  drugs/ghb/street-names drugs/ghb/street-names