All you wanted to know about laboratory tests, but were afraid to ask By Dietmar Stöckl STT Consulting The informed patient meeting the laboratory director Metrology Measurand 1

All you wanted to know about laboratory tests Metrology Without your husband? It will be boaring he said! We should understand the basics, I said! Otherwise, we may be lost from the start. You have a point there.

All you wanted to know about laboratory tests VIM – The metrologist’s bible International vocabulary of metrology (VIM) It’s all about measurement Measurand Quantity intended to be measured Quantity format: “System–Component (analyte); Kind of quantity” Serum–creatinine; amount-of- substance concentration, x µmol/L I knew it was thunderstorms!

All you wanted to know about laboratory tests Measurand S-creatinine Alkaline picrate active substances! (Jaffe) Creatinine! (Enzymatic) I knew it was thunderstorms!

All you wanted to know about laboratory tests Measurand It's CREATININE! Quantity intended to be measured NO! All clinical studies were with Jaffe! It's CREATININE! eGFR: trueness-based just introduced

All you wanted to know about laboratory tests Measurand It's CREATININE, I type I knew why I did'nt want to come!

All you wanted to know about laboratory tests The next visit Thyroid stimulating hormone (TSH) More about measurands

All you wanted to know about laboratory tests Resources ISO/IEC Guide 99:2007. International vocabulary of metrology – Basic and general concepts and associated terms (VIM). International Organization for Standardization: Geneva, 2007 (VIM = Vocabulaire International de Métrologie). JCGM 200:2008. International vocabulary of metrology – Basic and general concepts and associated terms (VIM). International Bureau of Weights and Measures (BIPM); Joint Committee for Guides in Metrology (JCGM): Paris, Freely available at: See also, Clinical and Laboratory Standards Institute (CLSI): nologyDatabase/Harmonized_Terminolo.htm