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What is Biology ? Study of Life Bios- =life -logy = study of 2

Major Branches of Biology: 1.Botany Plant Biology 2.Zoology Study of animals What makes something alive? Think/Pair/Share LAB……………………. 3 Cytology: Genetics: Ecology:

Characteristics of Living Things 1. Made up of Cells - Multi- or uni- 2. Can reproduce 3. Grow and Develop 4. Obtain & use material for energy 5. Maintain a stable internal environment Homeostasis Metabolism 4 Textbook pgs

Characteristics of Living Things 6. Based on a universal genetic code 7. Change over time 8. Response to their Environment 5 Evolution DNA

Cells 6

Reproduction Asexual Reproduction  Asexual reproduction is the formation of new individuals from the cell(s) of a  Asexual reproduction is the formation of new individuals from the cell(s) of a single parent.  It is very common in plants; less so in animals. Sexual Reproduction  Sexual reproduction is the formation of new individuals from the fusion of gametes.  Two parents 7

Metabolism Sum of all of the chemical reactions in the body. Breakdown and build up. 8

Universal Genetic Material DNA Information passed from parent to offspring 9

Characteristics of Living Things 1. Made Up of Cells 2. Reproduce 3. Are Based on a Genetic Code 4. Growth and Development 5. Need for Materials and Energy 6. Response to the Environment 7. Maintaining Internal Balance 8. Evolution 10

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Organic Chemistry Study of Compounds that contain Carbon.Study of Compounds that contain Carbon. Why is carbon so interesting?Why is carbon so interesting? 1-Carbon has 4 valence electrons. 2-Carbon has the ability to form more compounds than any other element. 13

CARBON SKELETONS CREATES DIVERSITY 14

What are we composed of? - We have structure- 15 Elements Covalent bonds Atoms Compounds Macromolecules Cell Proteins Lipids Carbohydrates Nucleic acid Carbon compounds Functional groups Nucleus DNA Ribosomes Endomembrane Organelles

Macromolecules of Life4 basic Molecules 1.C arbohydrates 2.L ipids 3.P roteins 4.N ucleic Acids 16

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18 Carbohydrates = Sugars

Carbohydrates 2 main functions 1) Provide energy to living cells. –Main Source of energy. 2) Structural Components -cell walls CHO 1:2:1 ratioCHO 1:2:1 ratio The name carbohydrate means "watered carbon" or carbon with attached water molecules.The name carbohydrate means "watered carbon" or carbon with attached water molecules. 19

Vocabulary Check Monomer- Single unit Polymer- many units 20 Many molecules are made of up one or more smaller units.

This is PAUL LEMUR. He's a lemur named Paul. JOKE BREAK 21

Monosaccharides one sugar unit Glucose - plants make during photosynthesis Galactose -milk C 6 H 12 O 6 22 Apple Juice RNA Simple sugars

Disacchrides two sugars What molecule will this make? 23 Complex sugar

Sucrose Table Sugar Plants transport sugarDisacchrides 24

Polysaccharides Glycogen (pictured)Glycogen (pictured) Glycogen functions as a fuel store in animals. - Large amounts are stored in liver and muscle and maintain circulating blood glucose levels between meals.Glycogen functions as a fuel store in animals. - Large amounts are stored in liver and muscle and maintain circulating blood glucose levels between meals. 25 “Many sugars”“Many sugars” Complex sugar

26Polysaccharides “Many sugars”“Many sugars”

Starch- plants store sugars in this form.Starch- plants store sugars in this form. Viewed under a microscope, the starch grains in these plants cells are visible as small dots. 27

Energy Carbohydrates store energy in their chemical bonds. Your body breaks down the sugars to get energy. Animation 28

Plant Cell Walls Cellulose 29 Structure

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Long-term Energy Storage Long-term Energy Storage More carbon-hydrogen (C-H) bonds than carbohydrates. More carbon-hydrogen (C-H) bonds than carbohydrates. Commonly called fats, oils, and waxes. Commonly called fats, oils, and waxes. They are insoluble in water due to the nonpolarity of the molecules. They are insoluble in water due to the nonpolarity of the molecules. Make good cell membranes. Make good cell membranes. Lipids Overview 32 C, H, O

Cells use lipids for: Cells use lipids for: Long-term energy storage. Long-term energy storage. Cushions & Insulation. Cushions & Insulation. Protective coatings & Waterproofing Protective coatings & Waterproofing Cell membranes (Phospholipids). Cell membranes (Phospholipids). Examples: Fats, oils, waxes Fats, oils, waxes Cutin in plants. It helps the plants retain water. Cutin in plants. It helps the plants retain water. 33

Structure of Lipids Glycerol backbone w/ 3 fatty acid chainsGlycerol backbone w/ 3 fatty acid chains 34Glycerol fatty acid chains ENERGY stored in the C-H bonds!

Lipids “don’t like” water. Phospholipids & Membrane Structure 35

36 Saturated Fat -No double bonds, so they lay flat. "the enemy" -Solid at room Temperature Unsaturated Fat -Double bonds, so they DO NOT lay flat. "the good guys"! -Liquid at room Temperature

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Nucleic acids are complex macro- molecules that store genetic information in cells in the form of a code. 38

39 Function: Stores and transmits genetic information Two TYPES of nucleic acids – 1. DNA (deoxyribonucleic acid) – double strand of genetic information 2. RNA (ribonucleic acid) – single strand copy of DNA used to build proteins NUCLEIC ACIDS C, H, O, N, P

Nucleotides (monomers) have 3 parts: 1.A phosphate group 2.A sugar 3.A base. 40 Polymers of nucleotides Stores and transmits genetic information

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Proteins Functions Transport molecules Hemoglobin transports oxygen Storage molecules Iron stored in the liver in a protein complex Mechanical support Skin, bones, hair, & nails contain collagen Hormones Enzymes Speed up chemical reactions Helps control metabolism. Immune System Antibodies in the immune system 42 C, H, O, N, S

Proteins-Structure Elements: CHONSElements: CHONS Made of small units called Amino AcidsMade of small units called Amino Acids 43 Amino Acids

44 Bonds that holds Amino Acids together is called a Peptide Bond.

Protein can be large complex molecules. 45 Function of a protein depends on shape and its ability to recognize and bind to some other molecule.

Denaturing Proteins pH, salt, temp, etc. are altered, protein may unravel and lose its conformation 46

Can have fatal consequences. Ex: Inherited disease, sickle cell anemia, results from a single incorrect amino acid at the 6th position of a protein chain out of 146. When the amino acid sequesnce is wrong: Sickle Cell Anemia: 47

…are PROTEINS!!!!!! 48

Enzymes are proteins Enzymes speed up chemical reaction. These reaction would take place anyway…enzymes just speed them up! 49

Without an enzyme! With an enzyme! 50

How do ENZYMES work? 1.The enzyme attaches to one or more of the reactants in a reaction. 2.The reactants that bind to the enzyme are known as the substrates. 3.The part of the enzyme where the substrate attaches to the enzyme is called the active site. 4.The shape of the active site only fits the shape of the substrate, somewhat like a lock fits a key. In this way only the correct substrate binds to the enzyme. 51

52 Active Site

Reactants/ Substrates Enzyme Enzymes can only bind to certain substrates this is known as the Lock-and-Key Mechanism. When the reaction is over the Enzyme is left as it was. 53 Animation

Once the enzyme and substrate are together, the enzyme holds the substrate so the reaction can occur. Once the reaction is over, the enzyme unlocks the product and the enzyme can start a new reaction with an identical substrate. Enzymes are not permanently changed or used up in reactions 54 Animation

Reaction pathway without enzyme Activation energy without enzyme Activation energy with enzyme Reaction pathway with enzyme Reactants Products Effect of Enzymes Go to Section: Enzymes work by LOWERING the amount of energy required for the reaction to proceed. 55

How do you speed up enzymes? 1.Add more of the enzyme. 2.Warm up the enzyme! Don’t warm it too much or it may denature and stop working. 56

change in the pH A change in the pH of the enzyme can cause a change in the shape of the active site, therefore changing the activity of the enzyme. 57 Animation

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Each Chemical reaction in your body is helped along by a different enzyme. Enzymes have 4 special features in common do not 1. They do not make processes happen that would not take place on their own. They just make the processes take place faster! 2. Enzymes are not permanently altered or used up in reactions. 3. The same enzyme works for the forward and reverse directions of a reaction. 4 Each enzyme is highly selective about its substrate. 54 Review Website