Sepsis Alert – Clinical Decision Support Maternal Newborn eHR

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Presentation transcript:

Sepsis Alert – Clinical Decision Support Maternal Newborn eHR Richard A Greene Maternal Newborn Clinical Management System National Project Team,

Outline Sepsis Clinical Decision Support Some Evidence The MNCMS Project Sepsis Alert Base criteria Function Documentation

Sepsis Sepsis is an uncontrolled inflammatory response to an infection. The systemic inflammatory response syndrome (SIRS) may be triggered by an infection, trauma, burn, or other offenses Treatment delay – rapid advance to septic shock, multiple organ dysfunction syndrome (MODS), and death. Estimated 5-year mortality rate for patients with severe sepsis is about 60%; Survivors experience much lower physical quality of life Interval from diagnosis to treatment affects short- and long-term patient outcome

Screening tool – Early recognition of sepsis Twice daily screening – Surgical ICU Pulse, Temp, RR and WCC Each abnormal scores 1 Score of 4 Identify Source Intensivist advised - ? Commence sepsis protocol Sepsis mortality decreased 33% (35% down to 23%) Moore J et al, J Trauma, 2012

Electronic tool – Sepsis identification Randomized trial – ICU setting Detection SIRS – alert to the physician via eHR No management advice or recommendations 442 patients over 4 months Feasible/Safe Interventions and outcomes (LOS, Mortality) – no difference Hooper M et al, Crit Care Med, 2012 Alert, no decision support

Alert System and Goal directed therapy Training on alert and Sepsis bundle Sepsis Management Alert Response Team – Code SMART Med (CC), Sepsis nurse, Resp Technician, Pharmacist No differences in positive cultures, infection source, Shock Significant Improvement in Sepsis Bundle compliance Significant reduction in sepsis related mortality La Rosa JA et al, Crit Care Res Pract, 2012

Evaluation for sepsis—screening Tool. (3) Are any of the following organ dysfunction criteria present AND acute:  □ SBP < 90 mmHg or MAP < 65 mmHg  □ SBP decrease >40 mmHg from baseline  □ Bilateral pulmonary infiltrates with a new (or increased) oxygen requirement to maintain SpO2 > 90%  □ Creatinine > 2 mg/dL or Urine Output < 0.5 mL/kg/hr for more than 2 hours  □ Bilirubin > 2 mg/dL  □ Platelet count <100,000  □ Coagulopathy (INR > 1.5 or aPTT > 60 secs)  □ Serum lactate > 2 mmol/L   ➢If suspicion of infection is present AND organ dysfunction is present, the patient meets criteria for Severe sepsis.   ➢If patient meets Severe sepsis criteria, AND has refractory hypotension (>60 min AND/OR unresponsive to fluid bolus of   20 mL/kg), the patient meets criteria for Septic shock. Initiate and complete the severe sepsis protocol. Instructions: Use this screening tool to screen patients for sepsis. (1) Is the patient's history suggestive of a new infection:  □ no  □ yes, if yes suspected source   □ Pneumonia, empyema   □ Urinary tract infection   □ Acute abdominal infection   □ Meningitis   □ Skin/soft tissue infection   □ Bone/joint infection   □ Wound infection   □ Bloodstream catheter infection   □ Endocarditis   □ Implantable device   □ Other (2) Are any two signs and symptoms of infection present AND new to the patient?  □ Hyperthermia (>101°F or 38.3°C)  □ Hypothermia (<96.8°F or 36°C)  □ Tachycardia (>90 bpm)  □ Tachypnea (>20 bpm)  □ Acutely altered mental status  □ Leukocytosis (WBC count >12,000)  □ Leukopenia (WBC count <4,000)  □ >10% immature neutrophils If the answer is yes to both questions 1 and 2, suspicion of infection is present:  □ Obtain: serum lactate, blood cultures, CBC with diff, basic chemistry labs, bilirubin  □ Pertinent diagnostic tests ___________________________________

HAVE YOU HEARD ABOUT MN-CMS? Maternal Newborn Clinical Management System

Description and benefits The MN-CMS Project is the design and implementation of an electronic health record (EHR) for all women and babies in maternity services in Ireland. This record will allow all information to be shared with relevant providers of care as and when required. The key benefits include: Improved patient care as a result of better communication, supported decision making and effective planning of care. More effective and efficient recording of information reflecting best standards in documentation. Enhanced clinical audit and research locally as a result of better quality data. Informed business intelligence that will drive local and national management decisions.

Objectives of MN-CMS project The core objective of the MN-CMS project is to implement Cerner’s Millennium product (Millennium) in all 19 maternity hospitals in Ireland. Millennium is a highly scalable system and will be configured to meet the main objective of the HSE, namely to have a single national centralised database for Maternity and Neonatal services in Ireland.  Other key objectives include;  Implement a fully integrated maternal and newborn clinical management system to support the business and service objectives of the Hospital. Phase out of the paper chart into MN-CMS. Integrate MN-CMS with all required 3rd party systems Implement the necessary infrastructure to support the project. Train all staff required to use the system in an appropriate manner. Maintenance & Support.

Clinical Decision Support for early Recognition of Sepsis 5 hospitals General hospital population 6200 patient admissions CDS began silent surveillance when a patient’s initial diagnostics were in their EHR. The sepsis CDS methodology captured results, clinical events, and time stamps. 817 (13%) patients screened-in – 51% not yet recognized by staff Identified 379/459 sepsis patients (Sens 82%; PPV 46%) Of the 5383 patients without an alert, 80 patients had a sepsis-associated discharge code 5303 true negatives and 80 false negatives (99% NPR) Amland RC & Hahn-Cover KE, Am J Med Qual, 2014

Clinical Decision Support in an eHealth Record Sepsis program enabled by computerized CDS and a cloud-based surveillance capability expedited recognition reduced ICU services improved in-hospital survival increased likelihood of discharge home in patients with sepsis. Amland R et al, J Hosp Med(pending)

Commercial Provider of Millennium - MNCMS Sepsis Recognition Commercial Provider of Millennium - MNCMS

Diagnostic Criteria - Pregnancy

Discern Alert - SIRS

Reminder & Direct link to documentation

Medical log in:

Diagnosis – once documented - Coded

Sepsis Alert and Clinical Decision Support Should aid early recognition of Sepsis Especially in a low risk group where sepsis is more likely to be ‘missed’ Will enhance response to a diagnosis of sepsis Alerts and support orientated documentation Will allow audit of sepsis in maternity services Will allow assessment of the criteria which have not been validated for maternity patients

Questions/comments r.greene@ucc.ie Thank You! Questions/comments r.greene@ucc.ie