Nichino America Inc. Jim Adams, Manager, Product Development Marie Maks-Regulatory Affairs Manager Phone: (302) Web site: IR-4 Food Use Workshop Sacramento, CA
NAI EC NAI SC Tolfenpyrad
Chemical Details on Tolfenpyrad Chemical Name: 4-chloro-3-ethyl-1-methyl-N-[4-p- tolyloxy)benzyl] pyrazole -5-carboxamide Empirical Formula: C 21 H 22 Cl N 3 O 2 Molecular Weight: Code Number: NAI-2302
Insects Controlled Hemiptera, Coleoptera, Diptera, Lepidoptera, Thysanoptera, and Acarina Poisoning by ingestion; contact activity; anti-feeding activity against leps Target Crops: Vegetables, Cucurbits, Cole Crops Fruits & Nuts Selected row crops Ornamentals
Efficacy Trials Use rate to lb. a.i/acre ( grams ai / hectare) 14 – 27 oz/a (15% EC and 15% SC formulations) Alternative mode of action useful against numerous vegetable and fruit/nut pests
U.S. Registration Timeline Submit non-crop indoor greenhouse use mid 2008 as reduced risk candidate Submit crop uses with residue chemistry data by 2010 as reduced risk candidate
NNI-0771 NNI-0772 NNI-0776 Flubendiamide-Based Insecticides
2009 Introductions NNI-0772 (Tourismo™) Tree Nuts, Pome, Stone, Vines, Cotton NNI-0871 (Vetica™) Vegetables, Cucurbits, Cole Crops
US Registration Timeline Submission to EPA 2008 Commercial Launch 2009
NNI-0101 Pyrifluquinazon
Pyrifluquinazon (NNI-0101) Hemiptera / Homptera Rates: grams ai/hectare Whitefly, Aphids Rates: grams ai/hectare Mealybug, thrips, leafhopper Higher Rates: Scale True bugs
Biological mode of action on aphids Hours after treatment Percent of dispersal insects (stop feeding) & mortality Abnormal behavior Death by starvation Appearance of activity/Green peach aphid Figure 1. Mortality and percent of insect dispersal from treated plants of green peach aphid, Myzus persicae, after treatment with NNI-0101 at a dose rate of 50ppm. (insects may appear normal) of NNI-0101 treated insects NNI-0101 shows two distinct effects on aphids; 1. Rapid response of abnormal behavior (insect dispersion, feeding cessation) 2. Slow lethal action
Possible IR-4 Interests Onion thrips (PCR submitted) Aphid, Thrip, Whitefly, Mealybug and Scale control on ornamentals Rapid cessation of whitefly and aphid feeding reduces transmission of viruses vectored by these pests on important fruit and vegetable crops
US Registration Timeline Submit for food crop uses early 2010