Normal cell cycle DNA replication Doughter cells G2 phase Nuclear division Cytokinesis 1x.

Slides:



Advertisements
Similar presentations
LN #15 Cancer & Cell Cycle. The Cell Cycle Interphase –Period of cell growth and DNA replication Mitosis –Period of cell division Prophase, metaphase,
Advertisements

Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!
Alterations in the Cell Cycle and Gene Mutations that Cause Cancer
Chapter 6 Section 2 The Cell Cycle Grade 10 Biology Fall 2010.
Cancer: a genetic disease of inherited and somatic mutations n Gene mutations and/or genetic instability are involved in many cancers. n Viruses and environmental.
AP Biology Regulation of Cell Division.
9.3 Cell Cycle Regulation Objectives: 5(A) describe the stages of the cell cycle, including deoxyribonucleic acid (DNA) replication and mitosis, and the.
Cancer- A Deeper Look (Part 4) Ms. Gaynor Honors Genetics.
How Cells Divide Chapter 11.
AP Biology Regulation of Cell Division.
The Cell Cycle Day 3. Cancer: Out of Control Cell Division The defining feature of a cancerous cell is that is divides much more often than is healthy-
Cell Cycle and Mitosis 9.1 Cell Cycle. What is the cell cycle?  Repeating series of events  Five stages  Interphase (3 parts)  G 1  S  G 2  M phase.
9.3 Cell Cycle Regulation Objectives Review Vocabulary
Genetics of Cancer Genetic Mutations that Lead to Uncontrolled Cell Growth.
1 How Cells Divide Chapter Outline Cell Division in Prokaryotes Discovery of Chromosomes Structure of Chromosomes Phases of the Cell Cycle Interphase.
Chapter 12: The Cell Cycle
CELL CYCLE.
Introduction Histone deacetylases(HDACs)  modulating chromatin accessibility during transcription, replication, recombination and repair;  required.
The Cell Cycle 5.1.
Genetics of Cancer Genetic Mutations that Lead to Uncontrolled Cell Growth.
9.3 Cell Cycle Regulation Cellular Reproduction Normal Cell Cycle  Different cyclin/CDK combinations signal cell activities, including DNA replication,
The Cell Cycle. When do cells divide? Reproduction Replacement of damaged cells Growth of new cells In replacement and growth cell divisions how should.
Part II.
Part IV and Chapter 11 Biology Sixth Edition Raven/Johnson (c) The McGraw-Hill Companies, Inc.
Cell Cycle Control and Cancer What happens when things go wrong?
Cancer. Cancer is a disease of the cell cycle Caused by one or more of the following: Increase in growth signals Loss of inhibitory signals In addition,
Subtitle Cell Cycle Regulation. Timing and rate of cell division are important Rate of cell division varies depending on cell type Cell cycle is controlled.
Cell Cycle Analysis Questions
Cell cycle 김다은 성균관대학교 / 약학과
Regulation of Cell Division and Cancer
Cell Cycle Essential Standards
p53 function and regulation in normal cells and cancer cells
Cell Cycle Regulation Normal Cell Cycle
Cell Cycle Regulation Normal Cell Cycle
Regulation of Cell Division
Alterations in the Cell Cycle and Gene Mutations that Cause Cancer
Homework from last class:
Chapter 6 Section 2 Cell Cycle.
B lymphocytes produce antibodies.
Losing Control of the Cell cycle
Chapter 12: The Cell Cycle
The Cell Life Cycle.
Chapter 9 Section 1 The Cell Cycle.
The Cell Cycle and Understanding Cancer
Cell Cycle Problems Checkpoints in the cell cycle will prevent division if: If the cell is short of nutrients If the DNA within the nucleus has not been.
BIOLOGY 12 Cancer.
Cancer- A Deeper Look (Part 4)
Chapter 12: The Cell Cycle
Why Do Cells Divide? Reproduction Growth Replacement of Tissues Repair.
Chapter 12: The Cell Cycle
Chapter 10.3 Section 3 Regulating The Cell Cycle Objectives
Chapter 6 Section 2 The Cell Cycle Objectives
Cell Cycle Practice Test
Why Do Cells Divide? Reproduction Growth Replacement of Tissues Repair.
Cell Cycle.
Cell Cycle Regulation Chapter 9 Section 3.
Cell Division.
3.2.5 Cell Cycle L.O: to state and describe the stages in the cell cycle to apply knowledge of the cell cycle to cancer treatment.
AP Biology The Cell Cycle.
Cytokinesis & Control Over Cell Division
Regulation of the Cell Cycle
Specific Tumor Suppressor Genes
Ratio of Surface Area to Volume
Members: Zenab, Venus, Irla AP Bio, Pd. 7&8
Why Do Cells Divide? Reproduction Growth Replacement of Tissues Repair.
Chapter 12: The Cell Cycle
Control of the Cell Cycle
Chapter 12: The Cell Cycle
Question #1 Which of the following is NOT a reason why interphase is necessary? It replicates DNA It doubles everything so the cell can split into identical.
Loss of Drp1 induces replication stress-mediated genome instability.
Presentation transcript:

Normal cell cycle DNA replication Doughter cells G2 phase Nuclear division Cytokinesis 1x

DNA damage STOP activation of p53 Checkpoint arrest DNA damage checkpoint

DNA repair, expression of Wip1, inactivation of p53 DNA damage START activation of p53 Recovery from the checkpoint after DNA repair

DNA damage Abnormally high level of Wip1 inactivation of p53 deficient checkpoint Genome instability Accumulation of mutations Cancer Transmission of Mutations to progeny Role of Wip1 oncogene in tumourigenesis 100x

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com. Inc. All rights reserved.