Immune System Day 4 "Treasure the love you receive above all. It will survive long after your good health has vanished." -Og MandinoOg Mandino
Today’s Agenda Finish Non-specific immunity notes Quiz Specific immunity notes—obj. 9, 10
Bacterial leprosy infection just under skin.
“border line leprosy—numb centers
2. Phagocytic cells-- macrophages i.Phagocytes include macrophages and neutrophils ii.Phagocytes engulf and destroy pathogens iii.Phagocytosis is enhanced when pathogens surface is altered by antibodies or complement proteins iv.Cell killing is enhanced by respiratory burst
Obj Natural killer cells – attack and lyse body cells infected by viruses or that are cancerous.
Obj. 7 Inflammatory response 1. Skin & mucous membranes 2. Phagocytic cells 3. Natural killer cells 4. Inflammatory response – damaged tissues release histamines –Histamines make vessels leaky, releasing phagocytes & clotting factors –Phagocytes engulf bacteria –Platelets form clots
Obj. 7
Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING 5. Antimicrobial substances –Interferon –Complement proteins
Obj. 8 Fever 1. Skin & mucous membranes 2. Phagocytic cells 3. Natural killer cells 4. Inflammatory response 5. Antimicrobial substances 6. Fever –Macrophages release pyrogens –Hypothalamus elevates temperature –Liver & spleen supply less iron –Bacteria don’t grow well without iron –Metabolism increases speeding repair
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Objective 9 B & T cells come from bone marrow. B’s mature in bursa (bone) T’s mature in thymus
Objective 10 Antigens are substances capable of causing an immune response.
variable region