Pulmonary Embolism Extraction Catheter Development Trip Cothren Lauren Nichols Dustin Temple Advised by: Dr. Michael Barnett, VUMC Cardiology.

Slides:

Advertisements

Similar presentations

Aortic dissection: current percutaneous options Advanced Angioplasty BSET Jan 2008.

Advertisements

The Cardiovascular System

Indicated for Arterial and Venous Embolizations in the Peripheral Vasculature April, 2004.

Lines and Tubes.

Redesign of a Distal Protection Filter for Carotid Artery Stenting

W e m a k e i d e a s c o m e a l i v e 001IHP For internal use only Not only a peripheral stent available in Renal sizes...

By Justin Martin.  The veins carry oxygen depleted blood back to the heart from the rest of the body.  In the legs, the veins have to fight gravity.

Coronary Stent Megan French. What is a Stent A small, mesh-like device made of metal Acts as a support or scaffold, in keeping the vessel open Stent helps.

Percutaneous Closure of Patent Foramen Ovale Sponsors: Kung Ming Jan, M.D., Ph.D. Judah Weinberger, M.D., Ph.D. Columbia University Medical Center Department.

Angioplasty’s Fight against Restenosis: Drug Eluting Stents & Bare Metal Stents.

INTRAVENOUS TECHNIQUES 1.To understand the proper indications for central intravenous access 2.To know how to perform central intravenous techniques during.

Stenting: Function, Problems, and Procedure. Uses for Stents  Peripheral artery disease (PAD)  Renal vascular hypertension  Hemodialysis access maintenance.

One stage coronary and peripheral intervention Pawel Buszman, MD, American Heart of Poland, Ustron Silesian Medical School, Katowice.

Intravascular Foreign Body Retrieval System Nathan Luibrand, Nicholas Luibrand, Lukas Richards, and Elise Adcock-Hinojosa Advised by Dr. Michael Barnett.

Angiography and Interventional Radiography Chapter 20.

Cardiovascular Implants. The total cost (direct and indirect) for CVD in the United States was almost 450 billion USD in 2008 CVD is also the leading.

3/10/2003 Patent Ductus Arteriosus Occlusion Device Oral Presentation #3 Group 6 David Brogan, Darci Phillips & Daniel Schultz Advisor: Dr. Thomas Doyle.

Human Heart & Circulatory System

Cardiac Catheters for Delivery of Cell Suspensions Donald Nick Jensen, DVM, MS Division of Cardiovascular Devices HHS/FDA/CDRH.

The Circulatory System. Aorta Superior vena cava Pulmonary artery Pulmonary vein Bicuspid valve Right atrium Right ventricle Inferior vena cava.

Confidential: Internal Use only 1 Click to edit Master title style Click to edit Master text styles – Second level Third level – Fourth level » Fifth level.

Medtronic CardioVascular Interventional Pipeline 1.

Pulmonary Flow Resistive Device Taya Furmanski Albert Attia Advisor: Thomas Doyle, M.D. April 9, 2003.

Pulmonary Embolism Pulmonary embolism is blockage in one or more arteries in your lungs. Maggie Trainor.

Intravascular Foreign Body Retrieval System Nathan Luibrand, Nicholas Luibrand, Lukas Richards, and Elise Adcock-Hinojosa Advised by Dr. Michael Barnett.

Circulatory diseases Arteriosclerosis Condition in which cholesterol or other fatty material becomes deposited under the inner lining of arteries. Fatty.

Intravascular Foreign Body Retrieval System Nathan Luibrand, Nicholas Luibrand, Lukas Richards, and Elise Adcock-Hinojosa Advised by Dr. Michael Barnett.

Alternative Approach Trans-Ulnar Approach Feasibility of Percutaneous Coronary Intervention Via Transulnar Artery Approach in Selected Patients with Coronary.

Circulation route Blood leaves the heart via the aorta (main artery) → body → returns to heart via vena cava (main vein) → right atrium → right ventricle.

Angiography and Interventional Radiography Chapter 17.

Cardiovascular System Vocab

Coronary Stents By: Brian Volpe. Coronary Heart Disease (CHD) is the narrowing and blockage of the coronary arteries that supply the heart with blood.

Clinical Needs Presentation Christopher Troiano RIT Mechanical Engineering.

Dissolvable Heart Stents Richard Melpignano. Coronary Heart Disease Coronary Heart Disease (CHD) is, as of 2012, the leading cause of death worldwide.

Cauterizing Biopsy Catheter for Percutaneous and/or Vascular Intervention Charles Blyth Cristina Fernandez Scott Hittinger Cameron Jones Brian McGee.

New strategies and perfusion/aspiration devices for primary PCI Sandra Garcia Cruset, PhD. Cordynamic B.U. Marketing Manager.

Pulmonary Embolism Extraction Catheter Development

The Circulatory System (Cardiovascular). Cardiovascular System Includes your heart, blood and vessels Includes your heart, blood and vessels Bring Oxygen.

Pulmonary Flow Resistive Device Taya Furmanski Albert Attia Advisor: Thomas Doyle, M.D. March 17, 2003.

Pulmonary Flow Resistive Device Taya Furmanski Albert Attia Advisor: Thomas Doyle, M.D. February 12, 2003.

Blood Vessel Notes. Arteries Carry blood away from the heart Thick walls- carry fast and furious rush of blood Elastic Very smooth- to help prevent clots.

Occlusion Device for Patent Ductus Arteriosus Christina Mathieson & Trung Nguyen Advisor: Dr. Tom Doyle BME 273 – Senior Design Project.

2/14/2003 Patent Ductus Arteriosus Occlusion Device Oral Presentation #2 Group 6 David Brogan, Darci Phillips & Daniel Schultz Advisor: Dr. Thomas Doyle.

Team Members: Lacey Halfen, Jessica Hause, Erin Main, Peter Strohm & Fan Wu Client: Orhan UnalAdvisor: Willis Tompkins Team Members: Lacey Halfen, Jessica.

Bard Denali Inferior Vena Cava Filter Fracture and Embolization Resulting in Cardiac Tamponade: A Device Failure Analysis William T. Kuo, MD, Scott W.

Determine method of rapid prototyping or plastic extrusion to create prototype of true-to-scale catheter Determine optimal slot size without affecting.

4/11/2003 Patent Ductus Arteriosus Occlusion Device Oral Presentation #4 Group 6 David Brogan, Darci Phillips & Daniel Schultz Advisor: Dr. Thomas Doyle.

Hip replacement - DePuy – Jonhson and Jonhson The Orthogenesis Limb Preservation System (LPS™) is a modular segmental replacement prosthesis system designed.

Endoluminal Closure Device January 25, 2006 Braham Dhillon Ali Hales Laura Mattaliano John Sticklen.

Open cervical approach for carotid artery stenting

Issues and Current Situations in the Development of Endovascular Treatment Devices for Pediatric Cardiology in the US – US Industry Dan Gutfinger, MD,

Regulatory Challenges for Bioabsorbable Stent Approval

Hina M. Pinto, MSE Scientific Reviewer

Successful retrieval of embolized atrial septal defect and patent foramen ovale closure device using novel coronary wire trap (CWT) technique. Alireza.

Percutaneous Closure of a Coronary Fistula

Advisors: Gary Byram, Ph.D.

DES Bioabsorbable and DCB Technologies

CRT 2012 Primer for Endovascular Interventions

Bio-Absorbable Stents to Encourage Growth in Brazil Peripheral Vascular Devices Market-Ken Research.

Robert J. Lederman et al. JIMG 2014;7:

Coronary Artery Disease 2

Minimally Invasive Compressional Assist Device

Patent Ductus Arteriosus Occlusion Device Oral Presentation #1

Failure modes of thoracic endografts: Prevention and management

NEW GENERATION STENT COBALT-CHROMIUM SIROLIMUS ELUTING STENT.

A) Pulmonary angiography, showing a stenosis in the subsegment of the 10th segmental artery (anterior view); b) the catheter is introduced into a web stenosis;

The American College of Cardiology Presented by Dr. A. Abazid

Endoluminal Closure Device

Drug-eluting coronary stent market overview

Presentation transcript:

Pulmonary Embolism Extraction Catheter Development Trip Cothren Lauren Nichols Dustin Temple Advised by: Dr. Michael Barnett, VUMC Cardiology

Problem There are over 600,000 cases of pulmonary embolisms annually in the United States, which result in nearly 60,000 fatalities. Systemic thrombolytics can be dangerous Need a catheter that can quickly and effectively remove pulmonary embolisms

Goals The goal of this project is to design a catheter that can efficiently remove an embolism from the pulmonary artery. The main goals of the project are: To research and evaluate current technology in pulmonary embolism extraction To design a catheter that can successfully remove embolisms percutaneously and completely without damage to the patient To produce a feasible prototype of our design

Our Design Combined ideas from multiple existing medical products Inferior vena cava filter Absorbable hemostat Local clot busting drug administration Security from multiple backups

Filter Based off inferior vena cava filter Umbrella-like device Expandable to various sizes Use of Nitinol

Nitinol Different Nickel/Titanium composition Can be easily annealed and set Is used in orthodontics Biocompatible Advantageous price and strength

Preliminary CAD

Surgicel or Gelita Material that attracts clots Oxidized cellulose polymer Used clinically for over 50 years Coat prongs of filter Prevent clots pieces from going downstream Made by Ethicon

Trellis Catheter Device Inflatable back-end “clot-catching” device Local drug delivery Use of guide wire

Design Parameters Approximately 2 m in length Umbrella-like filter that deploys from tip Device expands to15 mm in diameter Clot attracting material coating filter Local thrombolytic injection to break up clot

Function Parameters Time frame of < 1 hr Embolus located via x-ray angiography Typically done by interventional radiology or cardiothoracic For use when systemic thrombolytics are not viable option

Potential Problems Hemolysis causes release of adenosine when cells lyse Bradycardia or heart failure Renal failure Unpredictable thrombolytic tolerance Mechanical damage to vessel wall

Current Work Decide local thrombolytic elution Choose best type of Surgicel or Gelita Develop Nitinol usage Refine model using Pro Engineer

Future Work Meet with Dr. Barnett and Dr. Bream to discuss feasibility of ideas Calculate force of push of memory wire against vessel wall Ensure biocompatibility of all materials Meet with Ethicon sales representative

References /sidcath.jpg /sidcath.jpg ngiojet.jpg ngiojet.jpg o2.jpg