New Ways to Do Science (And Maybe Change the World) Stephen M. Maurer Goldman School of Public Policy

Coverage Curation Updating Responsiveness Open Science

Curated & Updated Coverage Computationally Powerful Responsiveness Open Science √ √ √ √ √ Academic Commercial

Swiss Prot Table of Isotopes

GDB HGMD

The SNP Consortium Mutations Database Initiative; Data Delivery, Content, Ads, Alert Services, etc.

Communities Governments A Chilling Effect?

Which Hybrids Are Acceptable? Social Scientists Can Help! Limits of Open Science Ideology vs. Institutions Cutting Across Sectors Money

Traffic Builders Advertisements Alert Services Data Delivery MDI

Updates & Embargoes “Premium” Versions “Reasonable” Academic Rates

A New Community Goal A New Research Institution Intervening in Commercial Sector Taking the Literature Seriously

Investment Based on Price Signal Elicits Private Information Moral Risk: Researchers Moral Risk: Sponsors Monopoly Pricing Are the Remaining Risks Manageable?

A New Mode of Production Why It Works Ideology Education Reputation Job Prospects In Silico Biology

History: The Sabin & Salk Vaccines Would Big Pharma Play? And Would It Matter?

Investment Based on Price Signal Elicits Private Information Moral Risk: Researchers Moral Risk: Sponsors Monopoly Pricing

Investment Based on Price Signal Elicits Private Information Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors √√√

Investment Based on Price Signal Elicits Private Information √√ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

Investment Based on Price Signal Elicits Private Information √√ √√ √ √ √ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

Investment Based on Price Signal Ideology Education Reputation Building Job Hunting Government & Foundations

Investment Based on Price Signal Elicits Private Information √√ √√ √ √ √ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

Avoids Monopoly Pricing Avoids Moral Risk: Sponsors √√ √ √

Investment Based on Price Signal Elicits Private Information √√ √√ √ √ √ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

Elicits Private Information √ Databases & Advice Good Will & Politics Price Discrimination

Investment Based on Price Signal Elicits Private Information √√ √√ √ √ √ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

Avoids Moral Risk: Researchers √ √ Existing Regulation

Investment Based on Price Signal Elicits Private Information √√ √√ √ √ √ Avoids Monopoly Pricing Avoids Moral Risk: Researchers Avoids Moral Risk: Sponsors

S. Maurer, “Inside the Anticommons: Academic Scientists’ Struggle to Commercialize Human Mutations Data, ,” preliminary version available at ipconf/maurer01.pdf S. Maurer, “Promoting and Disseminating Knowledge: The Public/Private Interface,” a report for US National Academy of Sciences (2002), available at urer_background_paper.html

Prof. Suzanne Scotchmer, UC Berkeley (Economics, Public Policy). “Procuring Knowledge,” NBER Working Paper 9903 Available at

Prof. Arti Rai, Duke University School of Law Prof. Andrej Sali, California Institute for Quantitative Biomedical Research, UC San Francisco

New Ways to Do Science (And Maybe Change the World) Stephen M. Maurer Goldman School of Public Policy