Definitions Mutation – any change in the genetic sequence.

Slides:

Advertisements

Similar presentations

ATG GAG GAA GAA GAT GAA GAG ATC TTA TCG TCT TCC GAT TGC GAC GAT TCC AGC GAT AGT TAC AAG GAT GAT TCT CAA GAT TCT GAA GGA GAA AAC GAT AAC CCT GAG TGC GAA.

Advertisements

Supplementary Fig.1: oligonucleotide primer sequences.

Gene Mutations Worksheet

Decoding DNA Worksheet

Mutations Section 12–4 This section describes and compares gene mutations and chromosomal mutations.

 Genetic Mutations Accelerated Biology. What is a Mutation?  A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA.

PART 1 - DNA REPLICATION PART 2 - TRANSCRIPTION AND TRANSLATION.

Mutations. Review Importance of the Protein Shape –The order of amino acids dictates the shape of the protein –The shape determines the function of the.

Genetic Mutations Muytatogns?.

Mutations Section Objectives for this section  Contrast gene mutations and chromosomal mutations.

12-4 MUTATIONS. I. KINDS OF MUTATIONS 1. Mutation- change in genetic material that can result from incorrect DNA replication 2. Point Mutations- gene.

GENE REGULATION Gene regulation: The ability of an organism to control which genes are transcribed in response to the environment.

Gene Mutations Changes to the nucleotide sequence of the genetic material of an organism. Changes to the nucleotide sequence of the genetic material of.

Mutations in DNA changes in the DNA sequence that can be inherited can have negative effects (a faulty gene for a trans- membrane protein leads to cystic.

Slide 1 of 24 Copyright Pearson Prentice Hall 12-4 Mutations 12–4 Mutations.

MUTATIONS. Mutations are heritable changes in genetic information Only mutation in the GAMETES can be passed on from generation to generation There can.

First lesson back TASK 1 – GOT THROUGH HW TRANSLATION QUESTIONS TASK 2 – REVISE TRANSCRIPTION AND TRANSLATION.

Slide 1 of 24 VIII MUTATIONS Mutations Types of Mutations:

End Show Slide 1 of 24 Copyright Pearson Prentice Hall 12-4 Mutations Outline 12–4: Mutations.

Slide 1 of 24 Copyright Pearson Prentice Hall Biology.

Example 1 DNA Triplet mRNA Codon tRNA anticodon A U A T A U G C G

Fantasy Mutations Reality. Mutations: a permanent and heritable change in the nucleotide sequence of a gene. Are caused by mutagens (x-rays and UV light)

DNA, RNA and Protein.

4.12 DNA and Mutations. Quick DNA Review Base pairing Base pairing.

Mutation. What you need to know How alteration of chromosome number or structurally altered chromosomes can cause genetic disorders How point mutations.

G AT GCTACAAT TCCAGCATTCG C RA CKING THE GENE TI CCODE.

Mutations: Definition: Changes in DNA in an organism. These changes can be problematic, can be helpful, or can have no effect. Mutations are what DRIVES.

DNA/GENE MUTATIONS.

“How does it affect the protein?”

Gene Mutations.

Bellringer Three consecutive bases in mRNA are known as what?

Supplementary information Table-S1 (Xiao)

Sequence – 5’ to 3’ Tm ˚C Genome Position HV68 TMER7 Δ mt. Forward

Gene Mutations.

Mutations Chapter 12-4.

Types of Mutations.

Gene Mutations.

Gene Mutations Essential Question: How do changes in the DNA nucleotide sequence affect the resulting protein?

Mutations (Ch. 17).

Gene Mutations Chromosome Mutations

Decode the following message.

Topic #3: Types of Mutations

Ch 12-4 Genetic Mutations.

Station 2 Protein Synethsis.

Copyright Pearson Prentice Hall

Genetic Mutations Karyotype: the number and visual appearance of the chromosomes in the cell nuclei of an organism or species.

Copyright Pearson Prentice Hall

Mutation Notes.

Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall

- And its affect on Protein synthesis

Mutations (Ch. 17).

C-Notes: Mutations Stnd: BI.4.c 10/23/13

Mutations The fat cat sad.

The fat cat ate the wee rat ???

Copyright Pearson Prentice Hall

12–4 Mutations 12-4 Mutations Copyright Pearson Prentice Hall.

Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall

Mutations: Changes in Genes

Presentation transcript:

Definitions Mutation – any change in the genetic sequence. Gene alteration – when a change in the genetic code changes the amino acid sequence Silent mutation- when a change in the genetic code doesn’t change the amino acid sequence

Kinds of mutations Point mutation – change in just one nucleotide AAA mutates to AAG Insertion mutation – change in sequence by adding one or more bases. Deletion mutation – change in sequence by taking out one or more bases. Frame shift mutation – the result of an insertion or deletion that moves the codons down and changes all the amino acids

Frame shift mutation example AAG TAG CAT ACT AAT AGC ATA CT_

Mutation Worksheet #1 Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: AGA GCG CTT AAA AGG Amino Acid sequence: Type of mutation: Point mutation Gene alteration: None

Mutation Worksheet #2 Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: AGA GCA CTT AAT AGG Amino Acid sequence: SER-ARG-GLU-LEU-SER Type of mutation: Point mutation Gene alteration: yes, but only one a.a.

Mutation Worksheet #3 Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: AGA CAC TTA AAA GG Amino Acid sequence: SER-VAL-ASP-PHE-___ Type of mutation: deletion; frame shift Gene alteration: yes, frame-shift

Mutation Worksheet #4 Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: AGA GCA ATC CCG TTC GGG CTT AAA AGG Amino Acid sequence: SER-ARG-STOP Type of mutation: insertion Gene alteration: yes, significant

Mutation Worksheet #5 Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: AGA GCA AAA AGG Amino Acid sequence: SER-ARG-PHE-SER Type of mutation: deletion Gene alteration: yes, missing an a.a.

6. When a point mutation results in the same amino acid sequence, is it still considered a mutation? Yes because a mutation is a change in the genetic code and it may or may not result in a change in the amino acid sequence. A mutation that doesn’t result in a change in the amino acid sequence is called a silent mutation

Mutation Worksheet # Original DNA: Amino Acid sequence AGA GCA CTT AAA AGG Amino Acid sequence SER-ARG-GLU-PHE-SER Mutated sequence: Amino Acid sequence: Type of mutation: Gene alteration: