完整營養補充劑對於血液透析患者營養及生理狀況 之影響

Effects of complete nutritional supplement on nutritional and physiological status in hemodialysis patients The present study was designed to evaluate the effect of complete nutritional supplement on selected nutritional and physiological variables in hemodialysis (HD) patients. Nineteen adult HD patients were on regular three times weekly HD for at least 3 months. Patients were followed for a 1-month baseline period, this was before an intervention period, during which, patients were asked to incorporate 100 g of complete nutritional supplement (providing 460 kcal and 18 g protein) daily for 1 month. Patients were reevaluated at third months. A 4 days dietary record was performed over baseline and intervention period. The main outcome measures including anthropometry, blood data, dietary intake, Kt/V, subjective scoring for appetite, and tolerance to supplement were obtained during the 3-month period. Patients incorporated mean 67g complete nutritional supplement over intervention period. This resulted in the energy intake rose to 30 kcal/kg body weight/day (P < 0.05). Following administration of complete nutritional supplement, there were significant increases in concentrations of serum total protein, transferrin, blood urea nitrogen and body fat (P < 0.05). Kt/V, subjective scoring for appetite, the concentrations of blood bicarbonate, and neutrophile count did not change during the study period. Complete nutritional supplement was shown to bring about a significant improvement in some selected nutritional markers such as serum total protein, transferrin, blood urea nitrogen and body fat in chronic HD patients, and does not effect the physiological variables of patients. The present study was designed to evaluate the effect of complete nutritional supplement on selected nutritional and physiological variables in hemodialysis (HD) patients. Nineteen adult HD patients were on regular three times weekly HD for at least 3 months. Patients were followed for a 1-month baseline period, this was before an intervention period, during which, patients were asked to incorporate 100 g of complete nutritional supplement (providing 460 kcal and 18 g protein) daily for 1 month. Patients were reevaluated at third months. A 4 days dietary record was performed over baseline and intervention period. The main outcome measures including anthropometry, blood data, dietary intake, Kt/V, subjective scoring for appetite, and tolerance to supplement were obtained during the 3-month period. Patients incorporated mean 67g complete nutritional supplement over intervention period. This resulted in the energy intake rose to 30 kcal/kg body weight/day (P < 0.05). Following administration of complete nutritional supplement, there were significant increases in concentrations of serum total protein, transferrin, blood urea nitrogen and body fat (P < 0.05). Kt/V, subjective scoring for appetite, the concentrations of blood bicarbonate, and neutrophile count did not change during the study period. Complete nutritional supplement was shown to bring about a significant improvement in some selected nutritional markers such as serum total protein, transferrin, blood urea nitrogen and body fat in chronic HD patients, and does not effect the physiological variables of patients.