Advanced Glaucoma and Cataract: Management Options Regenbogen Michael – Ichilov Amer Radgonde – Hadassah Ron Yonina – Beilinson Reyvitch Svetlana – Barsilai Chetrit Noa – Assaf Harof Blumenfeld Oren - Wolfson Kaplan Audrey
Definition Cataract: Visually significant Advanced glaucoma: Visual field loss Moderate-severe Inadequate lowering of target pressure
Cataract Glaucoma Both are age –related Increased cataract PXF antiglaucomatous medications
Prevalence of Visual Impairment in Older Americans
Goals of Treatment Improve VA Reach target IOP Free from drugs Preserve VF
Surgical options Glaucoma surgery Cataract surgery Combined surgery
Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
Glaucoma Surgery Trabeculectomy Non-penetrating filtering surgery Goniosynechiolysis Shunt device Endoscopic cyclophotocoagulation
Surgical options Trabeculectomy Cataract surgery Combined surgery
Stand alone Trabeculectomy Pros: Reduces IOP +++ phacotrabeculectomy or cataract extraction Caprioli J et al.Trans Am Ophthalmol Soc Cons: Cataractogeneous Higher complication rate (hypotony, significant chamber shallowing … ) AGIS investigators Arch Oph 2001
Cataract extraction alone Pros: Cataract extraction decreases IOP per se (ACG>PXF>OAG) Dimitrov et al. Clin Exp Ophthal 2001 Friedman et al. Ophthalmology 2002 Cons: 10% IOP spike By 2 yr. 30% IOP worse than preoperative status Rainer et al. J Cat Ref Surg 1999 Hayashi et al. J Cat Ref Surg 2001
Lens extraction in PAC Pre-Phaco/IOLPost-Phaco/IOL
Combined Surgery: Best Choice One procedure improves VA and reduces IOP Quality of life Cataract surgery post trabeculectomy: more bleb failure
Combined surgery : techniques ECCE / phaco ? One site vs. two sites Limbal or fornix based With/without MMC Phacotrabeculotomy 2 sites + MMC (Vass Curr Op. 2004)
Complications Infections Hypotony Cataract formation Transient IOP elevation CME Choroidal effusion Suprachoroidal hemorrhage Leakage/failure of bleb Blebitis Endophthalmitis
Cataract+ well controlled OAG Only cataract
Cataract + CACG CATARACT SURGERY ONLY
Cataract with uncontrolled OAG moderate damage Phacotrabeculectomy +/- MMC
Cataract + advanced glaucoma (low target IOP) Phacotrabeculectomy+MMC trabeculectomy+MMC
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