Ocular Candidiasis Rupesh Agrawal, Carlos Pavesio Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom

Ocular History  73, male, British  complaints of blurred vision  no pain, redness

General History  prolonged hospitalisation for systemic co-morbid conditions  diabetes,  hypertension

First Presentation - Fundus  VA: OD: 6/9, OS- 3ft  OD: retinal exudates  OS: vitreous haze with retinochoroidal lesion and pigmenatry changes

Immediate Investigation intravitreal tap – for gram stain, fungus intravitreal tap – for gram stain, fungus candida – positive candida – positive

Diagnosis  bilateral candida endophthalmitis with vitritis  based on  clinical findings  co-morbid conditions with prolonged hospitalisation  positive vitreous biopsy

Treatment systemic Amphotericin B (5mg/kg intravenously for 14 days) systemic Amphotericin B (5mg/kg intravenously for 14 days) vitreous tap with intravitreal injection of Amphotericin B (0.1ml of 10ug/ml – stat and was repeated after 48 hours vitreous tap with intravitreal injection of Amphotericin B (0.1ml of 10ug/ml – stat and was repeated after 48 hours

Follow-up - After six months  lesions completely resolved  VA recovered to 6/6 in OU

Final follow up – After 12 Months  anti fungal treatment for six weeks  OU: cataract surgery, no specific pre- or postoperative treatment  VA: 6/6 – OU  no AC cells, no flare, no fundus lesions