Dr Nikunj Bhatt

First line Defense:  Epidermis  Mucus Membranes  Mucus  Hairs  Cilia  Lacrimal appartus  lysosome  Saliva  Flow of Urine  Vagina Secretion  Defecation  Vomiting  Sebum  Perspiration  Gastric Juice Dr Nikunj Bhatt

Second line Defense:  Antimicrobial Protein  In Blood and Interstitial fluids  WBCs secretes Interferon  Stops replication  They are α, β,Y types Compliment System  promotes Phagocytosis Transferrin  Reduce Iron to inhibit growth of bacteria Dr Nikunj Bhatt

Natural Killer cells and phagocytosis:  5-10 % are NK [natural Killer] next to first line and Antimicrobial protein  Neutrophils and Macrophages: are two major Phagocytes has five phases  Chemotaxis  Adherence  Ingestion  Digestion  Killing Dr Nikunj Bhatt

 Inflammation:  Tissue damage  Redness,pain,heat and swelling Dr Nikunj Bhatt

 Maturation of t cells Dr Nikunj Bhatt

 Maturation of B cells Dr Nikunj Bhatt

 Antigen  Immunogenicity  Reactivity  Receptors  epitope Dr Nikunj Bhatt

 APCs [Antigen Presenting Cells] Dr Nikunj Bhatt

 Activation Proliferation and Differentiation of T cells Dr Nikunj Bhatt

 Activation Proliferation and Differentiation of B cells Dr Nikunj Bhatt