Oesophagus. Oesophagus - squamous cell carcinoma Multiple LOH Amplification of CMYC, EGFR, CYCLIN D1, HST1… Overexpression of Cyclin D1 LOH at 3p2; LOH.

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Presentation transcript:

Oesophagus

Oesophagus - squamous cell carcinoma Multiple LOH Amplification of CMYC, EGFR, CYCLIN D1, HST1… Overexpression of Cyclin D1 LOH at 3p2; LOH at 9p31 LOH 3p14 (FHIT); LOH 17q25 (TOC) TP53 mutations Normal oesophagusOesophagitis Low-grade High-grade InvasiveSCC intraephitelial neoplasia

Oesophagus -adenocarcinoma, Barret‘s oesophagus

Stomach

Helicobacter pylori

Stomach - tumors

Carcinoma of stomach

Signet ring adenocarcinoma

Well differentiated adenocarcinoma

Intestine

Hirschprung‘s disease, ileum

Diverticulosis of large intestine

Ulceration during DIC

Abdominal typhus

Pseudomembranous colitis

Crohn‘s disease and ulcerous colitis

Crohn‘s disease

Crohn‘s disease, granuloma

Ulcerous colitis, dysplasia of glands

Intestine - tumors

Polyp of intestine

Adenocarcinoma of large intestine

Adenocarcinoma of large intestine PAS staining

Malignant lymphoma, CD20+

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