Cell Cycle Regulation. Determining frequency of division Cell type (what type of cell is it) Organism’s stage of development Current state of organism.

Slides:



Advertisements
Similar presentations
Chapter 9 Slides PART 2 Cellular Reproduction. 2 Interphase Prophase Metaphase Anaphase Telophase Name the Mitotic Stages:
Advertisements

9.3 Cell Cycle Regulation Objectives: 5(A) describe the stages of the cell cycle, including deoxyribonucleic acid (DNA) replication and mitosis, and the.
The normal cell cycle is regulated by cyclin proteins. Section 3: Cell Cycle Regulation K What I Know W What I Want to Find Out L What I Learned.
WHAT YOU WILL LEARN 9.3 CELL CYCLE REGULATION
Ch. 9.3 – Cell Cycle Regulation
Chapter 5.3. Factors Cell division is controlled by external and internal factors. If cells weren’t controlled in some way, they would likely grow out.
AP Biology Regulation of Cell Division AP Biology 1.Coordination of cell division a. A multicellular organism needs to coordinate cell division across.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
. Cell Division- Regulation of the Cell Cycle. Target #25-I can explain the external factors that are involved in cell cycle regulation Both external.
Cell Cycle Regulation Chapter 9 Section 3.
We learned that cells have a cycle of growth and division Skin cells like this one grow divide and eventually die over a period of about two weeks. These.
Biology I Section 9.3 SQ3R Quiz
Cell Growth and Division. Why do cells divide? DNA “Overload” DNA “Overload” –Not enough information for a big cell Exchanging Materials Exchanging Materials.
9.3 Cell Cycle Regulation Objectives –Summarize the role of cyclin proteins in controlling the cell cycle. –Explain how cancer relates to the cell cycle.
Cell Reproduction. Why Cells Divide Cell death Repair of injury Growth/development Maintains cell size.
9-3 CELL CYCLE REGULATION. Normal Cell Cycle Proteins called cyclins bind to enzymes called cyclin- dependent kinases (CDK) and signal cell reproduction.
9.3 Cell Cycle Regulation Objectives Review Vocabulary
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Regulation of Cell Division Coordination of cell division A multicellular organism needs to coordinate cell division across different tissues & organs.
9.3 Cell Cycle Regulation Cellular Reproduction Normal Cell Cycle  Different cyclin/CDK combinations signal cell activities, including DNA replication,
Cellular Reproduction.  As the cell grows, its volume increases much more rapidly than the surface area.  The cell might have difficulty supplying.
Cell Cycle Regulation. The Cell Cycle What can be learned from this experiment? There are different signals (proteins) present that aid in the progression.
Cell Cycle Regulation and Cancer
Section 9-3 Normal Cell Cycle  Different cyclin/CDK combinations signal other activities, including DNA replication, protein synthesis, and nuclear.
5.3 Regulation of the Cell Cycle TEKS 5A, 5B, 5C, 5D, 9C The student is expected to: 5A describe the stages of the cell cycle, including deoxyribonucleic.
Fun Fact! There are over 200 different types of cells in the human body, each performing specific functions!
Click on a lesson name to select. Chapter 9 Cellular Reproduction Section 1: Cellular Growth Section 2: Mitosis and Cytokinesis Section 3: Cell Cycle.
Subtitle Cell Cycle Regulation. Timing and rate of cell division are important Rate of cell division varies depending on cell type Cell cycle is controlled.
CANCER  how does it happen?. Checkpoints  Where a cell Normally checks its self for a mutation as it goes through cell cycle.
5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Ch. 9 Vocabulary Advanced Biology. Cell Cycle – A cycle in which cells reproduce by growing and dividing Interphase – The stage during which the cell.
Main Idea The normal cell cycle is regulated by cyclin proteins.
Do Now  If you have not already handed in your WebQuest packet, bring it to my desk.  Make sure your name is on it!
Copyright © by Holt, Rinehart and Winston. All rights reserved. ResourcesChapter menu CANCER how does it happen?
Cellular Reproduction
Section 3: Cell Cycle Regulation
Lecture 36 Cancer Ozgur Unal
Cell Cycle Regulation Normal Cell Cycle
Cell Cycle Regulation Normal Cell Cycle
Unit 5: Cell Growth and Development 5.3 Control of the Cell Cycle
The student is expected to: 5A describe the stages of the cell cycle, including deoxyribonucleic acid (DNA) replication and mitosis, and the importance.
Abnormal Cell Cycle: Cancer
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Cell Cycle Regulation 9.3.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Section 3: Cell Cycle Regulation
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
The Cell Cycle and Understanding Cancer
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Section 3: Cell Cycle Regulation
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Notes: Regulating the Cell Cycle
10.3 Regulating the Cell Cycle
Jeopardy Final Jeopardy Interphase M Stages Structures Regulation
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
9.3 Cell Cycle Regulation Normal Cell Cycle
Section 3: Cell Cycle Regulation
10.3 Regulating the Cell Cycle
Cell Cycle Regulation Chapter 9 Section 3.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Sec Notes Cell Cycle Continued.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Cell Differentiation/Stem Cells
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Predict: What would happen if the cell cycle failed
KEY CONCEPT Cell cycle regulation is necessary for healthy growth.
Presentation transcript:

Cell Cycle Regulation

Determining frequency of division Cell type (what type of cell is it) Organism’s stage of development Current state of organism

Controlling division Protein, enzyme interactions Cell environment

Cyclin ~Proteins~ Produced during different stages of cell cycle Bind with enzymes

Cyclin-dependent Kinase Cyclin binds with them This binding allows cell cycle to progress **Evolutionarily conserved**

Enzyme-Protein interaction Different interactions control different stages of the cycle

Checkpoints between G 1 & S between G 2 & pro between Meta & Ana If any mistake is noted, cycle stops

Apoptosis Programmed cell death Cell shrinks Releases proteins calling for phagocytes billion die each day!!!

When it goes wrong Cancer

Uncontrolled growth and division of cells Occurs due to mutations, frequently in the CDKs Cell cycle becomes unregulated Apoptosis stops Cells proliferate

Cancer proliferation Cancer cells do not remain in interphase Reproduce more rapidly than normal cells Outcompete for resources Choke off normal cells, tissue/organ no longer functions

Causes Toxins such as Carcinogens Put harmful molecules in body that cause mutations Cells that divide frequently

Repairing what was lost Stem Cell Research

Stem Cells Unspecified cells that develop into specialized cells By placing near specialized cells, they will adopt the same specialization

Embryonic Stem Cells After fertilization, cells have not specialized Specialize based on position and intercommunication

Adult Stem Cells Post-development (differentiation has occurred) Located in different areas of the body (Pancreas, bone marrow, nasal cavity) Take on function of tissue they enter

Differences Nobody dies with adult stem cells Far greater success with adult stem cells Typically used on the same person who donated