“KEYHOLE” CRANIOTOMY EARLIER MORE EXTENSIVE
Ultrasound Guided Aspiration +/- Thrombolytic Agent
DECOMPRESSIVE CRANIECTOMY FOR ICH Decompressive Craniectomy +/- evacuation of ICH Improve ICP, hemodynamics and metabolic parameters Murthy et al: Neurocrit. Care pxs, GCS 5-8, 92% survived 54.5% good outcome Schaller et al; Brain Res 2003 May be better with evacuation of ICH? Dierssen et al ACTA Neurochirg 1983
Decompressive Craniectomy Most minimally invasive?
OCCLUSIVE STROKE Intracranial Stenosis Intraarterial Thrombolysis Angioplasty with stenting EC-IC Bypass for chronic ischemia Predicted to increase in numbers Need to retrain the neurosurgeons Indications Skills
62/f Neurologist INTRAARTERIAL THROMBOLYSIS (rTPA) on the 6 th hour L MCA Occlusion
10 th hour 30 th hour
Angioplasty with IC Stent
IMPLICATION OF INTRAVASCULAR FOREIGN BODIES?
MALIGNANT MCA INFARCTION DECOMPRESSIVE CRANIECTOMY
DECOMPRESSIVE HEMICRANIECTOMY EFFECT ON ICP AND PtiO2 ICP PtiO2
Decompressive Craniectomy Increasing in acceptance and usage PGH: Site of RCT Only one ongoing as of now Factors to increase good outcome Younger (55 y) Earlier (<48 hrs) Non fulminant course /Dilemna of doing it too early or too late
Decompressive Craniectomy HeMMI: Hemicraniectomy for Malignant Middle Cerebral Artery Infarcts. Jamora,R, Chua, A., Collantes, E., Manila/Philippines Year started2004 Study size actual26 (12 Medical) Study size planned56 Age15-65 Timing of surgery<72 hrs
Decompressive Craniectomy RCT s in Hemicraniectomy Improved survival Is this enough? For most families it is