Service, Dissemination & Training CIBC CIBC Service, Dissemination, and Training Steve Corbató Associate Director, SCI Institute University of Utah CIBC EAB Meeting Salt Lake City 18 August 2006 Steve Corbató Associate Director, SCI Institute University of Utah CIBC EAB Meeting Salt Lake City 18 August 2006

Service, Dissemination & Training CIBC CIBC organization

Service, Dissemination & Training CIBC Overview - I Service Collaborator and general user support Computational resource access Verification & validation Regression testing (BioPSE) New development requests Mailing lists and web presence

Service, Dissemination & Training CIBC Overview - II Dissemination BioPSE and map3d software –Release planning and schedule –Documentation –Datasets & models Conferences, workshops & papers Training Student (undergrad, MS, PhD) Post-doctoral Collaborations & workshops

Service, Dissemination & Training CIBC Service Software Releases map3d (6.3) – Fully open source –MIT open source license –Ongoing development - Next release soon (Intel/OSX system support) –500 downloads over last year SCIRun/BioPSE ( – 9/2005) –BioImage PowerApp added –Windows & Mac OSX 10.4 releases –CMAKE use –1,200 downloads over last year

Service, Dissemination & Training CIBC Dissemination Publications – 2006 (14) G. Adluru, E.V.R. DiBella. “Segmentation Based Registration of Myocardium in Cardiac Perfusion Images,” In Proceedings of The 14th Annual Scientific Meeting of The International Society for Magnetic Resonance in Medicine (ISMRM), pp. (Accepted) G. Adluru, E.V.R. DiBella, R.T. Whitaker. “Automatic Segmentation of Cardiac Short Axis Slices in Perfusion MRI,” In Proceedings of The 2006 IEEE International Symposium on Biomedical Imaging, pp. (Accepted) S.P. Awate, R.T. Whitaker. “Unsupervised, Information-Theoretic, Adaptive Image Filtering for Image Restoration,” In IEEE Trans. Pattern Anal. & Mach. Intel., Vol. 28, No. 3, pp March, S. Babaeizadeh, D.H. Brooks. “Imaging Error from Mislocation of Surface Sensors: Sensitivity, Detection, and Estimate Correction, with Application to EIT,” In Proceedings of the IEEE International Conference on Acoustics, Speech, and Signal Processing, Toulouse, France May, A. Ghodrati, A. Keely, G. Tadmor, R.S. MacLeod, D.H. Brooks. “A Wavefront-Based Constraint for Potential Surface Solutions in Inverse Electrocardiography,” In Proceedings of the 26th Annual International Conference of the IEEE EMBS, New York, NY, USA August, A. Ghodrati, D.H Brooks, G. Tadmor, R.S. MacLeod. “A Threshold-Based Method for Inverse Solutions to Reconstruct Complex Obstacles, with Application to the Inverse Problem of Electrocardiography,” In SIAM Conference on Imaging Science, Minneapolis, MN, USA May, A. Ghodrati, D.H. Brooks, G. Tadmor, R.S. MacLeod. “Wavefront-based Models for Inverse Electrocardiography,” In IEEE Trans Biomed. Eng., pp. (in press) A. Ghodrati, D.H. Brooks, G. Tadmor, R.S. MacLeod. “Lead Selection for Inverse Electrocardiography,” In IEEE Trans Biomed. Eng., pp. in press C.R. Johnson. “Computational Methods and Software for Bioelectric Field Problems,” In Biomedical Engineering Handbook, 2nd Edition, Vol. 1, Ch. 23, Edited by J.D. Bronzino, editor-in-chief, CRC Press, Boca Raton, pp C.R. Johnson, D.M. Weinstein. “Biomedical Computing and Visualization,” In Proceedings of the Twenty-Ninth Australasian Computer Science Conference (ACSC2006): Conferences in Research and Practice in Information Technology (CRPIT), Hobart, Australia, Vol. 48, Edited by Vladimir Estivill-Castro and Gill Dobbie, pp M. Jolley, J. Triedman, C.-F. Westin, D. Weinstein, R.S. MacLeod, D.H. Brooks. “Image Based Modeling of Defibrillation in Children,” In Proceedings of the 26th Annual International Conference of the IEEE EMBS, New York, NY, USA August, L. Lorenzo, R.S. MacLeod, R.T. Whitaker, G. Adluru, E.V.R. DiBella. “Level sets and Shape models for Segmentation of Cardiac Perfusion MRI,” In Proceedings of International Society for Optical Engineering (SPIE) Conference on Medical Imaging 2006, pp. (Accepted) Y. Serinagaoglu, D.H. Brooks, R.S. MacLeod. “Improved Performance of Bayesian Solutions for Inverse Electrocardiography Using Multiple Information Sources,” In IEEE Trans Biomed. Eng., pp. in press C.H. Wolters, A. Anwander, X. Tricoche, D.M. Weinstein, M.A. Koch, R.S. MacLeod. “Influence of Tissue Conductivity Anisotropy on EEG/MEG Field and Return Current Computation in a Realistic Head Model: A Simulation and Visualization Study Using High-Resolution Finite Element Modeling,” In Neuroimage, Vol. 30, No. 3, pp April, 2006.

Service, Dissemination & Training CIBC Dissemination Publications – 2005 (30) S.P. Awate, R.T. Whitaker. “Higher-Order Image Statistics for Unsupervised, Information-Theoretic, Adaptive, Image Filtering,” In Proceedings of the IEEE Int. Conf. Computer Vision and Pattern Recognition (CVPR), pp S.P. Awate, R.T. Whitaker. “Unsupervised, Information-Theoretic, Adaptive Image Filtering for Image Restoration,” In IEEE Trans. Pattern Anal. & Mach. Intel., pp. (accepted) S.P. Awate, R.T. Whitaker. “Nonparametric Neighborhood Statistics for MRI Denoising,” In In Proc. Int. Conf. Information Processing in Medical Imaging (IPMI), Lecture Notes in Computer Science, Vol. 3565, pp July, F. Calderero, A. Ghodrati, D.H. Brooks, G. Tadmor, R.S. MacLeod. “A Method to Reconstruct Activation Wavefronts Without Isotropy Assumptions Using a Level Sets Approach,” In Functional Imaging and Modeling of the Heart: Third International Workshop (FIMH 2005), Barcelona, June 2-4, pp S.E. Geneser, S. Choe, R.M. Kirby, R.S. MacLeod. “Influence of Organ Conductivity in ECG Forward Modeling: A Sensitivity Study Using 2D Stochastic Finite Elements,” In Proceedings of The Joint Meeting of The 5th International Conference on Bioelectromagnetism and The 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, pp. (accepted) A. Ghodrati, D.H. Brooks, G. Tadmor, B.B. Punske, R.S. MacLeod. “Wavefront-based Inverse Electrocardiography using an Evolving Curve State Vector and Phenomenological Propagation and Potential Models,” In Proceedings of The Joint Meeting of The 5th International Conference on Bioelectromagnetism and The 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, pp. (accepted) D. Gullmar, J.R. Reichenbach, A. Anwander, T. Knosche, C.H. Wolters, M. Eiselt, J. Haueisen. “Influence of Anisotropic Conductivity of the White Matter Tissue on EEG Source Reconstruction - An FEM Simulation Study,” In Int. J. Bioelectromag., Vol. 7, No. 1, pp C.D. Hansen, C.R. Johnson. “The Visualization Handbook,” Edited by C.D. Hansen and C.R. Johnson, Elsevier, B. Hopenfeld, J.G. Stinstra, R.S. MacLeod. “The Effect of Conductivity on ST-Segment Epicardial Potentials Arising from Subendocardial Ischemia,” In Annal. Biomed. Eng., Vol. 33, No. 6, pp “The Visualization Handbook,” E.G. Khölmovski, E.V.R. DiBella, A.A. Samsonov. “Accurate Assessment of the Arterial Input Function using MRI with Radial Sampling,” In Proceedings of the Society for Cardiovascular Magnetic Resonance (SCMR) 8th Annual Scientific Sessions, pp. (accepted) G.L. Kindlmann, D.M. Weinstein, G. Jones, C.R. Johnson, M.R. Capecchi, C. Keller. “Practical Vessel Imaging by Computed Tomography in Live Transgenic Mouse Models for Human Tumors,” In Journal of Molecular Imaging, Vol. 4, No. 4, pp J.M. Kniss, G. Kindlmann, C.D. Hansen. “Multidimentional Transfer Functions for Volume Rendering,” In The Visualization Handbook, Edited by C.D. Hansen and C.R. Johnson, Elsevier, pp The Visualization Handbook S. Lew, C. Wolters, K. Lee, S. Makeig, G. Worrell, R. MacLeod. “Epileptogenic Source Localization For Open Skull Head Model of Epilepsy By Independent Component Analysis And Inverse Dipole Fit Method Denoising,” In 1st Annual Mountain West Biomedical Enginnering Conference, R.S. MacLeod, D.H. Brooks. “Quantitative Electrocardiography: Two Steps Forward and One Step Back,” Presented at The Joint Meeting of The 5th International Conference on Bioelectromagnetism and The 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, R.S. MacLeod, B. Yilmaz, B.B. Punske, B. Taccardi, D.H. Brooks. “Epicardial Activation Mapping from Multielectrode Venous Catheters,” In J. Electrocardiol., pp. (in press) R.S. MacLeod, S. Shome, J.G. Sinstra, B.P. Punske, B. Hopenfeld. “Mechanisms of Ischemia-Induced ST-Segment Changes,” In J. Electrocardiol., pp. (in press) R.S. MacLeod. “Ischemia-Induced ST Changes and Arrhythmic Risk,” In International Congress on Electrocardiology, pp. (accepted) S.G. Parker, K. Zhang, K. Damevski, C.R. Johnson. “Integrating Component-Based Scientific Computing Software,” In Frontiers of Parallel Processing For Scientific Computing, Edited by M.A. Heroux, P. Raghavan, and H.D. Simon, pp. (accepted) A.A. Samsonov, E.V.R. DiBella, P. Kellman, E.G. Kholmovski, C.R. Johnson. “Adaptive k-t BLAST/k-t SENSE for Accelerating Cardiac Perfusion MRI,” In Proceedings of the Society for Cardiovascular Magnetic Resonance (SCMR) 8th Annual Scientific Sessions, pp G. Scheuermann, X. Tricoche. “Topological Methods for Flow Visualization,” In The Visualization Handbook, Edited by C.D. Hansen and C.R. Johnson, Elsevier, pp Y. Serinagaoglu, D.H. Brooks, and R.S. MacLeod. “Bayesian Solutions and Performance Analysis in Bioelectric Inverse Problems,” In IEEE Trans Biomed. Eng., pp. (in press) The Visualization Handbook J.G. Stinstra, B. Hopenfeld, R.S. MacLeod. “On the Passive Cardiac Conductivity,” In Annal. Biomed. Eng., pp. (accepted) J.G. Stinstra, D.M. Weinstein, B. Hopenfeld, C.S. Henriquez, R.S. MacLeod. “Software Challenges in the New Field of Integrated Cardiac Models,” In Proceedings of The Joint Meeting of The 5th International Conference on Bioelectromagnetism and The 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, pp. (accepted) B. Taccardi, B.B. Punske, F. Sachse, X. Tricoche, P. Colli-Franzone, L.F. Pavarino, C. Zabawa. “Intramural Activation and Repolarization Sequences in Canine Ventricles. Experimental and Simulation Studies,” In J. Electrocardiol., Vol. 38, No. 4, pp T. Tasdizen, S.P. Awate, R.T. Whitaker, N. Foster. “MRI Tissue Classification with Neighborhood Statistics: A Nonparametric, Entropy-Minimizing Approach,” In Proceedings of The 8th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), pp D.M. Weinstein, S.G. Parker, J. Simpson, K. Zimmerman, G. Jones. “Visualization in the SCIRun Problem-Solving Environment,” In The Visualization Handbook, Edited by C.D. Hansen and C.R. Johnson, Elsevier, pp The Visualization Handbook R.T. Whitaker. “Isosurfaces and Level-Sets,” In The Visualization Handbook, Edited by C.D. Hansen and C.R. Johnson, Elsevier, pp ISBN: XThe Visualization Handbook C.H. Wolters, A. Anwander, X. Tricoche, D. Weinstein, M.A. Koch, R.S. MacLeod. “Influence of Tissue Conductivity Anisotropy on EEG/MEG Field and Return Current Computation in a Realistic Head Model: A Simulation and Visualization Study Using High-Resolution Finite Element Modeling,” In NeuroImage, December, C. H. Wolters, A. Anwander, X. Tricoche, S. Lew, C.R. Johnson. “Influence of Local and Remote White Matter Conductivity Anisotropy for a Thalamic Source on EEG/MEG Field and Return Current Computation,” In Int.Journal of Bioelectromagnetism, pp. (Accepted) C.H. Wolters, A. Anwander, X. Tricoche, S. Lew, C.R. Johnson. “Influence of Local and Remote White Matter Conductivity Anisotropy for a Thalamic Source on EEG/MEG Field and Return Current Computation,” In Proceedings of The Joint Meeting of The 5th International Conference on Bioelectromagnetism and The 5th International Symposium on Noninvasive Functional Source Imaging within the Human Brain and Heart, pp. (accepted) B. Yilmaz, R.S. MacLeod, B.B. Punske, B. Taccardi, D.H. Brooks. “Training Set Selection for Statistical Estimation of Epicardial Activation Mapping from Intravenous Multielectrode Catheters,” In IEEE Trans Biomed. Eng., pp. (in press) S. Zhang, D.H. Laidlaw, G. Kindlmann. “Diffusion Tensor MRI Visualization,” In The Visualization Handbook, Edited by C.D. Hansen and C.R. Johnson, Elsevier, pp The Visualization Handbook

Service, Dissemination & Training CIBC Dissemination Conference participation NBCR booths (SC|05 – Seattle and Biophysical Society – SLC) New Web presence for CIBC Wikis External for updates & meeting notes – Internal for project management –Complementing Bugzilla and MS-Project

Service, Dissemination & Training CIBC Training Graduated Students (13) Saeed Babaeizadeh (ECE, NEU) - Ph.D. Chris Butson (BE) - Ph.D. (defending this month) Alireza Ghodrati (ECE, NEU) - Ph.D. Bruce Hopenfeld (BE) - Ph.D. Gordon Kindlmann (CS) - Ph.D. Lucas Lorenzo (BE) - M.S. Alexei Samsonov (Physics) - Ph.D. Yesim Serinagaoglu (ECE) - Ph.D. Andrew Shafer (CES) - M.S. Laura Traynor (BE) - M.S. Robert Van Uitert (CS) - Ph.D. David Weinstein (CS) - Ph.D. Kris Zyp (CS) - M.S.

Service, Dissemination & Training CIBC Training First under CIBC name April Salt Lake City 26 participants (drawn nationally) Foci Image processing and geometric modeling Simulation Visualization 1-on-1 interactions with CIBC staff

Service, Dissemination & Training CIBC NCRR Center Community Collaborators Document. Service Training ResearchService Bug Report. Courses/ Tutorials On-site Visits Mail List Web site Dissemination Publications Conf./ Booths Panels/ Tutorials Web site

Service, Dissemination & Training CIBC Warnock Engineering Building

Service, Dissemination & Training CIBC Warnock Engineering Building

Service, Dissemination & Training CIBC Warnock Engineering Building

Service, Dissemination & Training CIBC Warnock Engineering Building

Service, Dissemination & Training CIBC SCI Faculty Distinction IBM Faculty Award (Claudio Silva) IEEE VGTC Technical Achievement Award (Chuck Hansen) Elected Fellow of the AAAS (Chris) 14 Editorial Boards 2 Chaired Conferences or Workshops 35 Conference or Program Committees 17 National and International Advisory Boards 18 Keynote or Plenary Talks 2 Patents and 2 Patent Applications

Service, Dissemination & Training CIBC SCI Leadership President’s Council of Advisors in Science and Technology (PCAST) - Technical Advisory Committee on Information Technology President’s Information Technology Advisory Committee (PITAC) - Subcommittee on Computational Science NIH-NSF Visualization Research Challenges Report (Lead Editor) NSF Blue Ribbon Panel on Simulation Based Engineering Science (SBES) Computing Research Association (CRA) - NIH Workshop on Biomedical Computing (Chair) SIAM Report on Computational Science and Engineering Education President’s Council of Advisors in Science and Technology (PCAST) - Technical Advisory Committee on Information Technology President’s Information Technology Advisory Committee (PITAC) - Subcommittee on Computational Science NIH-NSF Visualization Research Challenges Report (Lead Editor) NSF Blue Ribbon Panel on Simulation Based Engineering Science (SBES) Computing Research Association (CRA) - NIH Workshop on Biomedical Computing (Chair) SIAM Report on Computational Science and Engineering Education

Service, Dissemination & Training CIBC National Reports - Impact events/SBES_Final_Report.pdf

Service, Dissemination & Training CIBC