This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC,

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This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/ /JRRD Slideshow Project DOI: /JRRD JSP Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion Natalia C. Rodrigues, PhD; Lívia Assis, PhD; Kelly R. Fernandes, MSc; Angela Magri; Daniel A. Ribeiro, PhD; Roberta Brunelli, MSc; Daniela C. C. Abreu, PhD; Ana Claudia M. Renno, PhD

This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/ /JRRD Slideshow Project DOI: /JRRD JSP Aim – Evaluate effects of 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibiales anterior (TA). Relevance – Studies have shown that laser irradiation favors regeneration of skeletal muscle, shortening inflammatory phase and accelerating proliferative and maturation phases of skeletal muscle regeneration.

This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/ /JRRD Slideshow Project DOI: /JRRD JSP Method 63 Wistar rats divided into: – Control group (CG). – 10 J/cm2 laser-treated group (G10). – 50 J/cm2 laser treated group (G50). Compared 10 and 50 J/cm 2 fluences 7, 14, and 21 d after cryolesion on TA through morphology and muscle tissue structure analysis. Inflammatory process, granulation tissue, tissue structure, number of blood vessels, and immunomarkers were evaluated histologically and by immunohistochemistry analysis.

This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/ /JRRD Slideshow Project DOI: /JRRD JSP Results Main finding: – Both laser-treated groups presented better histological pattern. Earlier recruitment of cell infiltrate Higher amount of newly formed muscle fiber. More organized muscle tissue structure at the lesion.

This article and any supplementary material should be cited as follows: Rodrigues NC, Assis L, Fernandes KR, Magri A, Ribeiro DA, Brunelli R, Abreu DC, Renno AC. Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion. J Rehabil Res Dev. 2013;50(6):985–96. dx.doi.org/ /JRRD Slideshow Project DOI: /JRRD JSP Conclusion Results suggest that LLLT, at both fluences, positively affects injured skeletal muscle in rats, accelerating muscle-regeneration process.