Danielle Greenwald Emily Lynch Period 4

Mitosis is the process of cell division which results in the production of two daughter cells from a single cell, identical to one another and to the original parent cell. Mitosis can be divided into the following four principals stages. Prophase Metaphase Anaphase Telophase Works Cited

 Nucleoli disappear  Chromatin fibers become more tightly coiled  Each duplicated chromosome appears as two identical sister chromatids joined at the centromere  Mitotic spindle forms in the cytoplasm Mitotic spindle  Centrosomes move away from each other Centrosomes  Nuclear envelope fragments  Spindle fibers extend from each pole toward the equator of the cell Spindle fibers  Kinetochore microtubules throw chromosomes into agitated motion Kinetochore  Nonkinetochore microtubules radiate from the poles toward the cells equator without attaching to chromosomes PICTURES DIAGRAM HOME

 Centrosomes at opposite poles of cell  Chromosomes convene on the metaphase plate  Centromeres of chromosomes align Centromeres  Chromatids of each chromosome are attached to kinetochore microtubules of the spindlekinetochore PICTURES DIAGRAM HOME

 Centromeres of each chromosome divide  Each chromatid is now a chromosome  Spindle moves the once- joined sisters toward opposite poles of the cell  Poles of the cell move farther apart  By the end, each pole has equivalent collections of chromosomes PICTURES DIAGRAM HOME

 Daughter nuclei begins to form at the two poles  Nucleoli reappear and chromatin fiber becomes less tightly coiled  Two identical daughter cells follows shortly after mitosis with cytokenesis cytokenesis HOME PICTURES DIAGRAM

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 Mitotic spindle - specific group of spindle fibers used in the process of mitosis  Centrosomes- an organelle that serves as the main microtubule organizing center of the animal cell as well as a regulator of cell-cycle progression  Spindle Fibers - An aggregate of microtubules that move chromosomes during cell division.  Kinetochores - the protein structure on chromosomes where the spindle fibers attach during division to pull the chromosomes apart  Centromeres- a region of DNA typically found near the middle of a chromosome where two identical sister chromatids come in contact. It is involved in cell division as the point of mitotic spindle.  Cytokenesis - the process in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells

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