PMID:15889139. Mutations in two, or more, genes IGI Mutations in a single gene IMP Biological Process: meiosis? homologous recombination?

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Presentation transcript:

PMID:

Mutations in two, or more, genes IGI Mutations in a single gene IMP Biological Process: meiosis? homologous recombination?

Physical interactions between proteins IPI Cellular Component: complex involving Sgs1p, Top3, and Rmi1p with: SGS1TOP3

Biological Process: S phase DNA damage checkpoint? IGI IMP with: TOF1MRC1CSM3RAD53

than wild type. IMP Biological Process: increased recombination?

IMP IGI SGS 1 with: Biological Process: S phase DNA damage checkpoint? response to DNA damage?

snip

Biological Process: meiosis? homologous recombination? Cellular Component: complex involving Sgs1p, Top3, and Rmi1p? S phase DNA damage checkpoint? response to DNA damage? increased recombination? Molecular Function: no information in this paper

Cellular Component: complex involving Sgs1p, Top3, and Rmi1p? snip Searching/browsing for an appropriate term did not identify a term which described this complex Request a New Term? Sgs1p/Top3 complex? RecQ helicase-Topo III complex

Physical interactions between proteins IPI Cellular Component: complex involving Sgs1p, Top3, and Rmi1p with: SGS1TOP3

Cellular Component: snip RecQ helicase-Topo III complex IPI with: SGS1TOP3 For RMI1 For SGS1 IPI with: RMI1TOP3 RecQ helicase-Topo III complex For TOP3 IPI with: RMI1SGS1 RecQ helicase-Topo III complex

Biological Process: meiosis? homologous recombination? S phase DNA damage checkpoint? response to DNA damage? increased recombination?

Biological Process: response to DNA damage stimulus

Biological Process: response to DNA damage stimulus IGI IMP with: TOF1MRC1 CSM3 RAD53

Molecular Function: no information in this paper Molecular function unknownND this is the only paper!

SGS1TOP3 Inferred from Mutant Phenotype TOF1MRC1 CSM3RAD