Effect of Bone Morphogenetic Protein-2-Expressing Muscle-Derived Cells on Healing of Critical-Sized Bone Defects in Mice by Joon Yung Lee, Douglas Musgrave,

Slides:

Advertisements

Similar presentations

Healing of a Critical-Sized Defect in the Rat Femur with Use of a Vascularized Periosteal Flap, a Biodegradable Matrix, and Bone Morphogenetic Protein.

Advertisements

Periprosthetic Humeral Fractures After Shoulder Arthroplasty by Sanjay Kumar, John W. Sperling, George H. Haidukewych, and Robert H. Cofield J Bone Joint.

Subtrochanteric Valgus Osteotomy for Chronically Dislocated, Painful Spastic Hips by Kathleen A. Hogan, Matthew Blake, and Richard H. Gross J Bone Joint.

Bone Morphogenetic Protein But Not Transforming Growth Factor-β Enchances Bone Formation in Canine Diaphyseal Nonunions Implanted with a Biodegradable.

Total Knee Arthroplasty in Juvenile Rheumatoid Arthritis by David H. Palmer, Kevin J. Mulhall, Corey A. Thompson, Erik P. Severson, Edward R.G. Santos,

Effects of Autologous Platelet-Rich Plasma on Cell Viability and Collagen Synthesis in Injured Human Anterior Cruciate Ligament by Louay Fallouh, Koichi.

Antibiotic Cement-Coated Nails for the Treatment of Infected Nonunions and Segmental Bone Defects by Raghuram Thonse, and Janet D. Conway J Bone Joint.

Avoiding Complications in the Treatment of Humeral Fractures by Jeffrey O. Anglen, Michael T. Archdeacon, Lisa K. Cannada, and Dolfi Herscovici J Bone.

Effectiveness and Safety of Tranexamic Acid in Reducing Blood Loss in Total Knee Arthroplasty: A Meta-Analysis by Zhi-Gao Yang, Wei-Ping Chen, and Li-Dong.

Prospective Comparison of 1.5 and 3.0-T MRI for Evaluating the Knee Menisci and ACL by Pieter Van Dyck, Filip M. Vanhoenacker, Valérie Lambrecht, Kristien.

Effectiveness of a Microvascular Surgery Training Curriculum for Orthopaedic Surgery Residents by Jia-Wei Kevin Ko, Alyssa Lorzano, and Adam J. Mirarchi.

Computer Navigation for Total Knee Arthroplasty Reduces Revision Rate for Patients Less Than Sixty-five Years of Age by Richard N. de Steiger, Yen-Liang.

Surgical Anatomy of the Supraclavicular Brachial Plexus by Sophia Leung, Dan A. Zlotolow, Scott H. Kozin, and Joshua M. Abzug J Bone Joint Surg Am Volume.

Chondroblastoma of Bone in the Extremities by Hairong Xu, Dylan Nugent, Hector L. Monforte, Odion T. Binitie, Yi Ding, G. Douglas Letson, David Cheong,

Application of Bone Morphogenetic Proteins in the Treatment of Clinical Oral and Maxillofacial Osseous Defects by Philip J. Boyne J Bone Joint Surg Am.

The Influence of Head Size and Sex on the Outcome of Birmingham Hip Resurfacing by Callum W. McBryde, Kanthan Theivendran, Andrew M.C. Thomas, Ronan B.C.

The Current State of Cervical and Lumbar Spinal Disc Arthroplasty by R. Douglas Orr, Paul D. Postak, Mircea Rosca, and A. Seth Greenwald J Bone Joint Surg.

Surgical Repair of Acute and Chronic Tibialis Anterior Tendon Ruptures by V. James Sammarco, G. James Sammarco, Carlo Henning, and Solomon Chaim J Bone.

Damage to Cobalt-Chromium Surfaces During Arthroscopy of Total Knee Replacements by Gregory E. Raab, Christopher M. Jobe, Paul A. Williams, and Qiang G.

Detection of Orthopaedic Implants in Vivo by Enhanced- Sensitivity, Walk-Through Metal Detectors by Miguel A. Ramirez, Edward K. Rodriguez, David Zurakowski,

Anti-Apoptotic Effects of Caspase Inhibitors on Rat Intervertebral Disc Cells by Jong-Beom Park, In-Chul Park, Sung-Jin Park, Hyeon-Ok Jin, Jin-Kyung Lee,

Scoliosis in Patients with Duchenne Muscular Dystrophy by Lori A. Karol J Bone Joint Surg Am Volume 89(suppl 1): February 1, 2007 ©2007 by The Journal.

The Effect of Implants Loaded with Autologous Mesenchymal Stem Cells on the Healing of Canine Segmental Bone Defects* by SCOTT P. BRUDER, KARL H. KRAUS,

Effect of Scapular Orientation on Shoulder Internal Impingement in a Cadaveric Model of the Cocking Phase of Throwing by Teruhisa Mihata, Bong Jae Jun,

Symposium - The Outcomes Movement in Orthopaedic Surgery: Where We Are and Where We Should Go by MARC F. SWIONTKOWSKI, JOSEPH A. BUCKWALTER, ROBERT B.

Geometry of Carriers Controlling Phenotypic Expression in BMP-Induced Osteogenesis and Chondrogenesis by Yoshinori Kuboki, Qiming Jin, and Hiroko Takita.

Ciprofloxacin Inhibition of Experimental Fracture-Healing* by P. M. HUDDLESTON, J. M. STECKELBERG, A. D. HANSSEN, M. S. ROUSE, M. E. BOLANDER, and R. PATEL.

Venous Thromboembolic Disease After Total Hip and Knee Arthroplasty by Steven B. Haas, Robert L. Barrack, Geoffrey Westrich, and Paul F. Lachiewicz J Bone.

Hypertrophy of Ligamentum Flavum in Lumbar Spinal Stenosis Associated with Increased Proteinase Inhibitor Concentration by Jong-Beom Park, Jin-Kyung Lee,

Intercellular Adhesion Molecule-1 (ICAM-1, CD54) Is Increased in Adhesive Capsulitis by Yang-Soo Kim, Jung-Man Kim, Yun-Gyoung Lee, Oak-Kee Hong, Hyuk-Sang.

Allograft-Prosthesis Composite for Revision of Catastrophic Failure of Total Elbow Arthroplasty by Pierre Mansat, Robert A. Adams, and Bernard F. Morrey.

Histological Changes in the Human Anterior Cruciate Ligament After Rupture* by M. M. Murray, S. D. Martin, T. L. Martin, and M. Spector J Bone Joint Surg.

Rapidly Growing Squamous-Cell Carcinoma of the Hand in a Renal Transplant Recipient by James Rose, Samuel Harms, and Jennifer Moriatis Wolf JBJS Case Connect.

Allogeneic Mesenchymal Stem Cells Regenerate Bone in a Critical-Sized Canine Segmental Defect by Treena Livingston Arinzeh, Susan J. Peter, Michael P.

Development of a Patient-Reported Measure of Function of the Knee* by JAMES J. IRRGANG, LYNN SNYDER-MACKLER, ROBERT S. WAINNER, FREDDIE H. FU, and CHRISTOPHER.

The Prevalence of and Specific Risk Factors for Venous Thromboembolic Disease Following Elective Spine Surgery by Jason M. Sansone, Alejandro Munoz del.

Level of Evidence in Orthopaedic Journals by William T. Obremskey, Nick Pappas, Emad Attallah-Wasif, Paul Tornetta, and Mohit Bhandari J Bone Joint Surg.

Evaluation of the Content and Accessibility of Web Sites for Accredited Orthopaedic Sports Medicine Fellowships by Mary K. Mulcahey, Michelle M. Gosselin,

Risk of Injury to the Superior Gluteal Nerve When Using a Proximal Incision for Insertion of a Piriformis-Entry Reamed Femoral Intramedullary Nail by Jason.

The Financial Impact of Orthopaedic Fellowship Training by Trevor Gaskill, Chad Cook, James Nunley, and R. Chad Mather J Bone Joint Surg Am Volume 91(7):

Augmentation of Tendon-to-Bone Healing by Kivanc Atesok, Freddie H. Fu, Megan R. Wolf, Mitsuo Ochi, Laith M. Jazrawi, M. Nedim Doral, James H. Lubowitz,

Nicotine Delays Tendon-to-Bone Healing in a Rat Shoulder Model by L.M. Galatz, M.J. Silva, S.Y. Rothermich, M.A. Zaegel, N. Havlioglu, and S. Thomopoulos.

Alumina-on-Alumina Total Hip Arthroplasty by Young-Kyun Lee, Yong-Chan Ha, Jeong Joon Yoo, Kyung-Hoi Koo, Kang Sup Yoon, and Hee Joong Kim J Bone Joint.

Recombinant Human Bone Morphogenetic Protein-2 Accelerates Healing in a Rabbit Ulnar Osteotomy Model by M. L. Bouxsein, T. J. Turek, C. A. Blake, D. D’Augusta,

Total Knee Arthroplasty in Patients with Ankylosing Spondylitis by Javad Parvizi, Gavan P. Duffy, and Robert T. Trousdale J Bone Joint Surg Am Volume 83(9):

The Effect of Ultra-High Molecular Weight Polyethylene Wear Debris on MG63 Osteosarcoma Cells in Vitro* by D. D. DEAN, Z. SCHWARTZ, Y. LIU, C. R. BLANCHARD,

The Natural Progression of Synovial Fluid White Blood-Cell Counts and the Percentage of Polymorphonuclear Cells After Primary Total Knee Arthroplasty by.

Severe Acute Respiratory Syndrome (SARS) in a Geriatric Patient with a Hip Fracture by Kwok Chuen Wong, Kwok Sui Leung, and Mamie Hui J Bone Joint Surg.

The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008 by Benjamin J. Miller, Xin Lu, and Peter Cram J Bone Joint.

Orthopaedic Surgeons’ View on Strategies for Improving Patient Safety by Stein J. Janssen, Teun Teunis, Thierry G. Guitton, David Ring, and James H. Herndon.

by James H. Dubberley, Kenneth J. Faber, Joy C. MacDermid, Stuart D

Percutaneous Autologous Bone-Marrow Grafting for Nonunions by Ph. Hernigou, A. Poignard, F. Beaujean, and H. Rouard J Bone Joint Surg Am Volume 87(7):

Reconstruction of Segmental Bone Defects Due to Chronic Osteomyelitis with Use of an External Fixator and an Intramedullary Nail by Levent Eralp, Mehmet.

Prognostic Indicators for Recurrent Symptoms After a Single Corticosteroid Injection for Carpal Tunnel Syndrome by Philip E. Blazar, W. Emerson Floyd,

Role of Cages in Revision Arthroplasty of the Acetabulum by Tatu J. Mäkinen, Paul Kuzyk, Oleg A. Safir, David Backstein, and Allan E. Gross J Bone Joint.

Variability in Spine Surgery Procedures Performed During Orthopaedic and Neurological Surgery Residency Training by Alan H. Daniels, Christopher P. Ames,

The Use of Bone Morphogenetic Protein in Lumbar Spine Surgery by Jeffrey A. Rihn, Charley Gates, Steven D. Glassman, Frank M. Phillips, James D. Schwender,

Lower-Extremity Peripheral Nerve Blocks in the Perioperative Pain Management of Orthopaedic Patients by Benjamin E. Stein, Umasuthan Srikumaran, Eric W.

Effects of Capsular Plication and Rotator Interval Closure in Simulated Multidirectional Shoulder Instability by Brian L. Shafer, Teruhisa Mihata, Michelle.

Spontaneous Healing of a Tear of the Anterior Cruciate Ligament. A Report of Two Cases* by MASAHIRO KUROSAKA, SHINICHI YOSHIYA, TOSHIYUKI MIZUNO, and KOSAKU.

Transfer of LacZ Marker Gene to the Meniscus* by HIDEYUKI GOTO, FRANKLIN D. SHULER, CHANIN LAMSAM, HANS D. MOLLER, CHRISTOPHER NIYIBIZI, FREDDIE H. FU,

Ultrasound Measurements of Torsions in the Tibia and Femur by David Hudson, Todd Royer, and James Richards J Bone Joint Surg Am Volume 88(1): January.

Temporary Internal Distraction as an Aid to Correction of Severe Scoliosis by Jacob M. Buchowski, David L. Skaggs, and Paul D. Sponseller JBJS Essent Surg.

Topics in Medical Economics: Health Care Rationing by Joseph Bernstein J Bone Joint Surg Am Volume 88(11): November 1, 2006 ©2006 by The Journal.

The Need for Increased Access to the U.S. Health-Care System by Jesse E. Bible, Richard S. Lee, and Gary E. Friedlaender J Bone Joint Surg Am Volume 91(2):

Cytotoxic Effect of Zoledronic Acid-Loaded Bone Cement on Giant Cell Tumor, Multiple Myeloma, and Renal Cell Carcinoma Cell Lines by Pawel Zwolak, J. Carlos.

An AOA Critical Issue: Aging of the North American Population: New Challenges for Orthopaedics* by Joseph A. Buckwalter, James D. Heckman, and David P.

Late Lateral Displacement of the Humeral Head after Closed Reduction of Glenohumeral Dislocation: A Sign of Vascular Injury. Report of a Case* by DAVID.

Time Trade-Off as a Measure of Health-Related Quality of Life: Long Bone Nonunions Have a Devastating Impact by Patrick C. Schottel, Daniel P. O’Connor,

Viscosupplementation for Osteoarthritis of the Knee by David Jevsevar, Patrick Donnelly, Gregory A. Brown, and Deborah S. Cummins J Bone Joint Surg Am.

Presentation transcript:

Effect of Bone Morphogenetic Protein-2-Expressing Muscle-Derived Cells on Healing of Critical-Sized Bone Defects in Mice by Joon Yung Lee, Douglas Musgrave, Dalip Pelinkovic, Kazumasa Fukushima, James Cummins, Arvydas Usas, Paul Robbins, Freddie H. Fu, and Johnny Huard J Bone Joint Surg Am Volume 83(7): July 1, 2001 ©2001 by The Journal of Bone and Joint Surgery, Inc.

The amount of BMP-2, as determined with ELISA (enzyme-linked immunosorbent assay), that was produced by muscle-derived cells transduced with adenovirus containing BMP-2 cDNA. Joon Yung Lee et al. J Bone Joint Surg Am 2001;83: ©2001 by The Journal of Bone and Joint Surgery, Inc.

Percent closure of the skull defects in the four groups. d = defect only (group 1), d/s = defect treated with collagen sponge (group 2), d/s/c = defect treated with collagen sponge and nontransduced cells (group 3), and d/s/c/b = defect treated with collage... Joon Yung Lee et al. J Bone Joint Surg Am 2001;83: ©2001 by The Journal of Bone and Joint Surgery, Inc.

A, Gross specimen from group 3 (defect [arrows] treated with collagen sponge and nontransduced cells). Joon Yung Lee et al. J Bone Joint Surg Am 2001;83: ©2001 by The Journal of Bone and Joint Surgery, Inc.

Von Kossa-stained specimens (magnification, 10). Joon Yung Lee et al. J Bone Joint Surg Am 2001;83: ©2001 by The Journal of Bone and Joint Surgery, Inc.

Fluorescent in situ hybridization (FISH) analysis of injected cells with use of the Y-chromosome- specific probe and co-localization with osteocalcin. Joon Yung Lee et al. J Bone Joint Surg Am 2001;83: ©2001 by The Journal of Bone and Joint Surgery, Inc.