Molecular Diagnostics Certificate Program January 23, 2008 Information Session

Introduction Terry Kotrla, MS, MT(ASCP)BB Capella University Trish Phelps, PhD University Colorado Boulder

Certificate Program The certificate consists of three courses, one offered each semester. Individuals who meet ASCP requirements can use the coursework as the foundation for taking the certification exam.

MLAB 2378 Fundamentals of Molecular Diagnostics This course provides a comprehensive overview of the fundamental principles of clinical molecular diagnostics and explores the use of molecular techniques in the diagnosis of disease. Offered ONLINE only in the Fall 16 week semester.

BlackBoard Online course delivery system. Will provide detailed information of what is required each week. You MUST be disciplined to participate in an online course. Write your schedule down for study time AND STICK TO IT.

MLAB 2479 Molecular Diagnostics Techniques An introduction to the theory and laboratory techniques in molecular biology with an emphasis on molecular diagnostics, including DNA replication, transcription, gene expression and regulation, recombinant DNA and RNA techniques. Lecture and lab on campus in the SPRING semester during the evening.

MLAB 2363 Molecular Diagnostics Clinical Apply the theory, concepts, and skills in the clinical setting. Assigned to local hospitals or clinics. 160 hours 120 hours at clinical site 40 hours on research paper

How Difficult are the Courses? These are college level courses covering a relatively complex topic. Review of basic genetic such as Mendelian genetics and concepts and principles of gene transmission. Review of nucleic acid structure and function. In depth coverage of molecular testing.

Techniques Principle and theory of all aspects of a molecular procedure. Application of knowledge for each element of a procedure Calculating Temperature of Melting Determining concentrations of reactants for a procedure. Determining the sequence of primers and probes for specific targets.

Techniques Either hands on, virtual or both Polymerase Chain Reaction (PCR) DNA hybridization Gel electrophoresis Restriction Fragment Length Polymorphism (RFLP) Blotting techniques Microarray Evaluation of controls to validate results

Other Components necessary to set up a molecular laboratory. Physical lay out especially as it concerns prevention of cross-contamination Equipment necessary

Applications Forensics Oncology Immunology Hematology Predictive Genetic Testing Immunohematology Pharcogenetics Molecular Virology

Resources A web page of resources has been started to give you an idea of what will be covered.

ASCP Certification This certificate will be the starting point for preparing for certification exam. Eligibility Exam Content Suggested reading

Application Process Complete an application. Pick up an “Information Session Attendance Form” Submit the following: Completed application Completed immunization form Information Session Attendance Form INCOMPLETE APPLICATIONS WILL NOT BE ACCEPTED

Class Selection Applicants from the clinical sites which sent letters of support of our grant to the governor’s office will have priority. Other applicants will be selected based on the date that the application is ACCEPTED by the Health Science admission’s office.

Health Science Admission’s Office Address: Room Webberville Rd., Austin, Phone Number: Toll Free

Terry Kotrla’s Contact Info Phone: BEST CONTACT IS

Questions???