2003-2004 Antineoplastics 1 February 2016 3:08 AM.

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Presentation transcript:

Antineoplastics 1 February :08 AM

Alemtuzumab Antineoplastic Anti-CD52 antibody

Aminoglutethimide Antineoplastic Immunosuppressive Glucocorticoid antagonist Aromatase inhibitor (decreases steroid synthesis)

Amsacrine Antineoplastic Miscellaneous

Anastrozole Antineoplastic Antiestrogen Aromatase inhibitor

L-asparaginase Antineoplastic Protein synthesis inhibitor

Azathioprine Immunosuppressive Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP)

Bleomycin Antineoplastic Natural product Antibiotic

Busulfan Antineoplastic Alkylating Agent

Carmustine (BCNU) Antineoplastic Alkylating Agent

Cisplatin Antineoplastic Miscellaneous Cross-linking agent

Cyclophosphamide Antineoplastic Alkylating Agent

Cyclosporine Immunosuppressive Antineoplastic Binds cyclophilin Inhibits calcineurin

Cyproterone acetate Antiandrogen Antineoplastic androgen receptor antagonist

Cytarabine (AraC) Antineoplastic Antimetabolite

Dacarbazine Antineoplastic Alkylating Agent

Dactinomycin Antineoplastic Natural product Antibiotic

Daunorubicin Antineoplastic Anthracycline antibiotic Natural product

Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory steroid Not by inhalation

Doxorubicin Antineoplastic Anthracycline antibiotic Natural product

Etoposide Antineoplastic Natural product Plant alkaloid

Exemestane Antineoplastic Antiestrogen Aromatase Inhibitor

5-Fluorouracil Antineoplastic Antimetabolite Thymidylate synthase inhibitor

Fulvestrant Antineoplastic Antiestrogen Estrogen receptor antagonist

Gemtuzumab Antineoplastic Anti-CD33 antibody

Goserelin Antineoplastic Gonadotropin releasing hormone (GnRH) agonist

Hydroxyurea Antineoplastic Miscellaneous Ribonucleotide reductase inhibitor

Ibritumomab Antineoplastic Anti-CD20 antibody

Imatinib Antineoplastic Miscellaneous Tyrosine kinase inhibitor

Interleukin 2 Cytokine Antineoplastic

Interleukin 11 Cytokine Antineoplastic (supporting agent)

Iressa Antineoplastic Miscellaneous Tyrosine kinase inhibitor

Letrozole Antineoplastic Antiestrogen Aromatase Inhibitor

Leucovorin Antineoplastic (supporting agent) Folic acid analogue (used in methotrexate rescue)

Leuprolide Antineoplastic Gonadotropin releasing hormone (GnRH) agonist

Lomustine (CCNU) Antineoplastic Alkylating Agent

Mechlorethamine Antineoplastic Alkylating Agent

Melphalan Antineoplastic Alkylating Agent

6-Mercaptopurine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

Mesna Antineoplastic (supporting agent) Prevent hemorrhagic cystitis due to cyclophosphamide

Methotrexate Immunosuppressive Antineoplastic Folic acid antagonist Dihydrofolate reductase inhibitor

Mitomycin C Antineoplastic Natural product Antibiotic

Paclitaxel Antineoplastic Natural product Plant alkaloid (taxane)

Pentostatin Antineoplastic Miscellaneous Enzyme inhibitor (blocks purine synthesis)

Rituxumab Antineoplastic Anti-CD20 antibody

Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

Thalidomide Antineoplastic Anti-angiogenic Anti-TNF  Leprosy (not antibiotic)

6-Thioguanine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

Thiotepa Antineoplastic Alkylating agent

Trastuzumab Antineoplastic Anti-HER2 antibody

Tumor necrosis factor  Cytokine Antineoplastic

Vinblastine Antineoplastic Vinca alkaloid Natural product

Vincristine Antineoplastic Vinca alkaloid Natural product