Effects of Verbal Working Memory Load on Corticocorical Connectivity Modeled by Path Analysis of Functional Magnetic Resonance Imaging Data Honey et al.

Slides:

Advertisements

Similar presentations

Figure Three-dimensional reconstruction of the left hemisphere of the human brain showing increased activity in ventrolateral area 45 during verbal.

Advertisements

A Computational Model of Emotional Influences on Visual Working Memory Related Neural Activity Nienke Korsten Nikos Fragopanagos John Taylor OFC DLPFC.

Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance imaging. By: Kent A Kiehl, Andra M Smith,

Real-time fMRI brain computer interfaces: Self- regulation of single brain regions to networks Sergio Ruiz, Korhan Buyukturkoglu, Mohit Rana, Niels Birbaumer,

Lexical Ambiguity in Sentence Comprehension By R. A. Mason & M. A. Just Brain Research 1146 (2007) Presented by Tatiana Luchkina.

Neuropsychology of Religious Experience James A. Van Slyke.

An fMRI investigation of covertly and overtly produced mono- and multisyllabic words. Shuster LI, Lemieux SK. Brain and Language 93 (2005):20-31.

心理 101 王雅慧 F OLLOWING THE C ROWD : B RAIN S UBSTRATES OF L ONG -T ERM M EMORY C ONFORMITY.

Principles of MRI Some terms: – Nuclear Magnetic Resonance (NMR) quantum property of protons energy absorbed when precession frequency.

Motor cortex Organization of motor cortex Motor cortical map Effect of cortical motor neuron activation on muscle contraction Population coding.

Sensory Memory and Working Memory. Sensory Memory Brief Iconic/echoic High capacity Pre-attentive Is there a Neural Correlate of Sensory Memory?

Why is HANDWriting Important (Richards et al., 2007)  Hands are the end organs of brain that produce motor output for acting on the world.  In the process.

Functional Magnetic Resonance Imaging Carol A. Seger Psychology Molecular, Cellular, and Integrative Neuroscience Michael Thaut Music, Theater, and Dance.

Research by Wagner et al Presented by Daehan Choi.

Playing Piano in the Mind – An fMRI study on music imagery and performance in pianists I.G. Meister, T. Krings, H. Foltys, B. Boroojerdi, M. Muller, R.

Aging Clinical Research Center Brain Imaging Studies: Gender Effects Ruth O’Hara Assistant Professor, Department of Psychiatry and Behavioral Sciences,

ANALYSIS OF fMRI DATA BASED ON NN-ARx MODELING Biscay-Lirio, R: Inst. of Cybernetics, Mathematics and Physics, Cuba Bosch-Bayard, J.: Cuban Neuroscience.

THE “WORKING MEMORY” APPROACH Baddeley & Hitch (1974) –Use articulatory suppression to interfere with some tasks, not others B doesn’t precede AB A –Develop.

FINSIG'05 25/8/2005 1Eini Niskanen, Dept. of Applied Physics, University of Kuopio Principal Component Regression Approach for Functional Connectivity.

Using PET. We ’ ve seen how PET measures brain activity We ’ ve seen how PET measures brain activity How can we use it to measure the “ mind ” that works.

Functional Connectivity in an fMRI Working Memory Task in High-functioning Autism (Koshino et al., 2005) Computational Modeling of Intelligence (Fri)

Briana Cassetta Kiehl, K. A., et al (2001). Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance.

Jeremy R. Gray, Christopher F. Chabris and Todd S. Braver Elaine Chan Neural mechanisms of general fluid intelligence.

Tracing pain pathways from stimulus to report Lauren Y. Atlas 1, Matthew Davidson 1, Niall Bolger 1, Kate Dahl 1, Martin Lindquist 2, Tor D. Wager 1 1.

Age effects on hippocampal functional connectivity during multifeatural encoding Chris Foster 1, Milton Picklesimer 1, Neil Mulligan, Ph.D. 1, and Kelly.

Brain plasticity: effects of judo practice on gray matter volume Wantuir FS Jacini Lab of Neuroimaging, Department of Neurology - University of Campinas.

Modelling, Analysis and Visualization of Brain Connectivity

Role of Working Memory in Visual Selective Attention de Fockert, Rees, Frith, Lavie (2001)

Pattern Classification of Attentional Control States S. G. Robison, D. N. Osherson, K. A. Norman, & J. D. Cohen Dept. of Psychology, Princeton University,

MVPD – Multivariate pattern decoding Christian Kaul MATLAB for Cognitive Neuroscience.

The Working Memory Model was first proposed by Baddeley and Hitch in They Carried out an investigation to investigate whether there are different.

When the brain is prepared to learn: Enhancing human learning using real- time fMRI Y, J. J. a, Hinds, O. b, Ofen, N. a, Thompson, T. W. b, Whitﬁeld-Gabrieli,

Articulatory Net I.2 Oct 14, 2015 – DAY 21

Ch. 5 Bayesian Treatment of Neuroimaging Data Will Penny and Karl Friston Ch. 5 Bayesian Treatment of Neuroimaging Data Will Penny and Karl Friston 18.

RIGHT PARIETAL CORTEX PLAYS A CRITICAL ROLE IN CHANGE BLINDNESS by Naser Aljundi.

Orienting Attention to Semantic Categories T Cristescu, JT Devlin, AC Nobre Dept. Experimental Psychology and FMRIB Centre, University of Oxford, Oxford,

FMRI and MR Spectroscopy. BOLD BOLD=Blood Oxygenation Level Dependant contrast Neurons at work use oxygen (carried by hemoglobin) 1-5 s. delay, peaks.

Working Memory Model To what extent does psychological research support this model of memory?

Modeling and Neuroscience (or ACT-R and fMRI) Jon M. Fincham Carnegie Mellon University, Pittsburgh, PA

Brain magnetic resonance imaging with contrast dependent on blood oxygenation Ogawa et al. PNAS (1990) 87:9868.

FMRI in Detection of Deception. What is functional Magnetic Resonance Imaging? A magnetic field is passed through the organ of interest, the brain, during.

Date of download: 5/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Organization of Cognitive Control Within the Lateral.

Date of download: 6/27/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Neural Correlates of Antinociception in Borderline.

Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Dysfunction of the Default Mode Network in Parkinson.

Functional Magnetic Resonance Imaging During Planning Before and After Cognitive- Behavioral Therapy in Pediatric Obsessive-Compulsive Disorder Chaim.

Motor cortex Organization of motor cortex Motor cortical map

Cannabis Use and Memory Brain Function in Adolescent Boys: A Cross-Sectional Multicenter Functional Magnetic Resonance Imaging Study Gerry Jager, Ph.D.,

Volume 20, Issue 5, Pages (May 1998)

Todd S Braver, Jeremy R Reynolds, David I Donaldson Neuron

Multiple Change Point Detection for Symmetric Positive Definite Matrices Dehan Kong University of Toronto JSM 2018 July 30, 2018.

Experimental Design in Functional Neuroimaging

Sequential effects of propofol on functional brain activation induced by auditory language processing: an event-related functional magnetic resonance.

Neurophysiology of “Working Memory”

Todd S Braver, Jeremy R Reynolds, David I Donaldson Neuron

Chapter 16 The Frontal Lobes.

Sing-Hang Cheung, Fang Fang, Sheng He, Gordon E. Legge Current Biology

Neural Correlates of Visual Working Memory

The Prefrontal Cortex—An Update

The Future of Memory: Remembering, Imagining, and the Brain

Volume 78, Issue 8, Pages (October 2010)

The Molecular and Systems Biology of Memory

Will Penny Wellcome Trust Centre for Neuroimaging,

Christian J. Fiebach, Jesse Rissman, Mark D'Esposito Neuron

A Neural Network Reflecting Decisions about Human Faces

Clinical Concepts Emerging from fMRI Functional Connectomics

An Upside to Reward Sensitivity: The Hippocampus Supports Enhanced Reinforcement Learning in Adolescence Juliet Y. Davidow, Karin Foerde, Adriana Galván,

Neuroimaging, Predictive approaches.

César F. Lima, Saloni Krishnan, Sophie K. Scott

Selective and coherent activity increases due to stimulation indicate functional distinctions between episodic memory networks by Sungshin Kim, Aneesha.

Volume 10, Issue 1, Pages (January 2000)

Presentation transcript:

Effects of Verbal Working Memory Load on Corticocorical Connectivity Modeled by Path Analysis of Functional Magnetic Resonance Imaging Data Honey et al (Fri) Computational Modeling of Intelligence Summarized by Joon Shik Kim

Blood Oxygen Level Dependent (BOLD) Signal Amount of oxygen molecules bound to hemoglobin. If a specific task is performed, related brain regions are activated and the need for more oxygen leads to BOLD signal increase.

Task In a control task, subjects viewed a series of 14 letters with an interstimulus interval of 2 s. Subjects pressed the mouse button if the currently presented letter was the same as that presented n trials previously. If n=1, we call the task as 1 back task. If n=2, 2 back task and if n=3, 3 back task.

Generation of fMRI time series

Brain Activation Maps

Structural Equation Modeling (SEM) (Bullmore et al., 2000) where q denotes the number of path coefficients to be estimated and C denotes the sample covariance.

Model by Automated Search

Path Coefficient

Significant Path Coefficient Right Left

Discussion (1/3) Manipulation of cognitive demand in a verbal working memory task is associated with concomitant changes in corticocortical connections. Under both 1-back and 2-back conditions, there was a significant connections from the left inferior frontal gyrus to the left posterior parietal cortex.

Discussion (2/3) The projection from the left inferior frontal gyrus to the left posterior parietal cortex may be important in mediating articulatory rehearsal. Increasing n from 1 to 2 increases the load on articulatory rehearsal. This manipulation was associated with the emergence of a second significant connection between the inferior frontal gyrus and posterior parietal cortex via SMA.

Discussion (3/3) Our model did not provide a good fit to the 3- back data. The change in functional integration induced by an increase in load from 2- to 3-back may require qualitative reconstruction of the path diagram. Enhanced prefrontoprefrontal connectivity under the 2-back condition may reflect greater demand for executive process.