ZPEC  Anissa Anindya Widjaja  Chua Geok Lin  Goh Yufen  Ho Ping Ping, Crystal  Kek Xing Yi  Peh Pi Chia Emily

Topic  Industry Pharmaceutical  Technology Vaccines

Introduction  Hepatitis is the inflammation of the liver. May be caused by bacterial or viral infection, parasitic infestation, alcohol, drugs, toxins, or transfusion of incompatible blood.  Although many cases of hepatitis are not a serious health threat, the disease can become chronic and sometimes lead to liver failure and death.

Invention  Invention: Hepatitis a, b-combined vaccine and its lyophilized preparation  Comprises of a properly attenuated live hepatitis A virus and a purified hepatitis B surface antigen  Produced by a recombinant Chinese Hamster Ovary (CHO) cell and/or recombinant yeast  The inflammation associated with hepatitis A virus and with hepatitis B virus can be prevented  Useful for administration to children who dislike having multiple injections

Patent Number  WO 2005/  Hepatitis a, b-combined vaccine and its lyophilized preparation.

Commercialization  Public Awareness through advertisements  Seminars for doctors and public  Availability to GPs and specialists  Affordable cost