The Chromosomal Theory of Inheritance: Chromosomes and genes are present as ______________________ homologous chromosomes ___________during meiosis ________________ restores chromosome number to ____________________ The _________________________ claims it is the chromosome that ___________ and _________independently.

In flies ________________ is dominant to ______________, and long wings _____________ are dominant to vestigial wings _____. What is the expected phenotypic ratio from a cross between a heterozygous gray, heterozygous normal winged fly with a black vestigial fly? ________________________ But what he got was….. Gene Linkage

What explains the non-Mendelian results? __________________________________ The traits are located on the _________________ and are _________ to each other that they are said to be ___________. If the traits are linked, then all of the offspring should resemble the parental types, black vestigial or gray normal. How did we get the recombinant traits of black, normal and gray vestigial?

Using Recombination Frequency to Map Traits _______________________ between black and vestigial traits is __________ Recombination frequency between cn and black is __________ Recombination between cn and vg is _________________ Map these traits on the chromosome.

Determine the order of genes along a chromosome based on the following recombination frequencies: A - B 8% A - C 28% A - D 25% B - C 20% B - D 33% _______________

CHROMOSOMAL MUTATIONS