Semahat Demir, Ph.D. Program Director Biomedical Engineering & Research to Aid Persons with Disabilities (BME/RAPD) Division of Bioengineering and Environmental Systems National Science Foundation BME- Innovation, Design and Entrepreneurship Alliance (IDEA) September 28, 2005 Baltimore, MD NSF Programs Fostering Innovation in Bioengineering

Outline Vision and strategic goals of NSF Vision and strategic goals of NSF NSF Merit Review Criteria NSF Merit Review Criteria NSF Disciplines NSF Disciplines NSF Programs that Foster Innovation in Bioengineering NSF Programs that Foster Innovation in Bioengineering Engineering Directorate Engineering Directorate Other Directorates Other Directorates Interagency Activity and Working Groups Interagency Activity and Working Groups Interagency Funding Programs for Bioengineering Interagency Funding Programs for Bioengineering Concluding Remarks Concluding Remarks

NSF Vision NSF: Where Discovery Begins Enabling the Nation’s future through discovery, learning and innovation. Enabling the Nation’s future through discovery, learning and innovation.

People – Develop a diverse, internationally competitive and globally-engaged workforce of scientists, engineers and well- prepared citizens People – Develop a diverse, internationally competitive and globally-engaged workforce of scientists, engineers and well- prepared citizens Ideas – Enable discovery across frontier of science and engineering connected to learning, innovation and service to society Ideas – Enable discovery across frontier of science and engineering connected to learning, innovation and service to society Tools – Provide broadly accessible, state- of-the-art information bases and shared research and education tools Tools – Provide broadly accessible, state- of-the-art information bases and shared research and education tools NSF’s Strategic Outcome Goals

NSF Merit Review Criteria Criteria include: Criteria include: What is the intellectual merit and quality of the proposed activity? What is the intellectual merit and quality of the proposed activity? What are the broader impacts of the proposed activity? What are the broader impacts of the proposed activity?

What is the intellectual merit of the proposed activity? Potential Considerations: How important is the proposed activity to advancing knowledge and understanding within its own field or across different fields? How important is the proposed activity to advancing knowledge and understanding within its own field or across different fields? How well qualified is the proposer (individual or team) to conduct the project? (If appropriate, the reviewer will comment on the quality of prior work.) How well qualified is the proposer (individual or team) to conduct the project? (If appropriate, the reviewer will comment on the quality of prior work.) To what extent does the proposed activity suggest and explore creative and original concepts? To what extent does the proposed activity suggest and explore creative and original concepts? How well conceived and organized is the proposed activity? How well conceived and organized is the proposed activity? Is there sufficient access to resources? Is there sufficient access to resources?

What are the broader impacts of the proposed activity? Potential Considerations: How well does the activity advance discovery and understanding while promoting teaching, training and learning? How well does the activity advance discovery and understanding while promoting teaching, training and learning? How well does the activity broaden the participation of underrepresented groups (e.g., gender, ethnicity, disability, geographic, etc.)? How well does the activity broaden the participation of underrepresented groups (e.g., gender, ethnicity, disability, geographic, etc.)? To what extent will it enhance the infrastructure for research and education, such as facilities, instrumentation, networks and partnerships? To what extent will it enhance the infrastructure for research and education, such as facilities, instrumentation, networks and partnerships? Will the results be disseminated broadly to enhance scientific and technological understanding? Will the results be disseminated broadly to enhance scientific and technological understanding? What may be the benefits of the proposed activity to society? What may be the benefits of the proposed activity to society?

Additional Criteria Specific to the solicitation Requirements and expectations Requirements and expectations Management plan Management plan Dissemination plan Dissemination plan

NSF Disciplines & Structure 1)Biological Sciences (BIO) 2)Computer and Information Sciences and Engineering (CISE) 3)Education and Human Resources (EHR) 4)Engineering (ENG) 5)Geosciences (GEO) 6)Mathematical and Physical Sciences (MPS) 7)Social, Behavioral And Economic Sciences (SBES) 8)Polar Programs 9)Cyberinfrastructure

Engineering (ENG) Directorate ENG Divisions 1.Bioengineering & Environmental Systems (BES) —Biomedical Eng & Research to Aid Persons with Disabilities (BME/RAPD) Program 2.Civil & Mechanical Systems (CMS) 3.Chemical and Transport Systems (CTS) 4.Design and Manufacturing Innovation (DMI) —Grant Opportunities For Academic Liaison with Industry (GOALI) 5.Electrical & Communications Systems (ECS) 6.Engineering Education & Centers (EEC) —Engineering Research Centers (ERC) —Partnership for Innovation Program —Industry/University Cooperative Research Centers Program Office of Industrial Innovation (OII) Small Business Innovation Research (SBIR) and Small Business Technology Transfer Program (STTR)Small Business Innovation Research (SBIR) and Small Business Technology Transfer Program (STTR)

BME/RAPD Program Fostering Innovation CAREER, investigator-initiated, SGER projects CAREER, investigator-initiated, SGER projects High risk high return projects High risk high return projects Funding of BME Senior Design Projects Funding of BME Senior Design Projects Funding of BME- Innovation, Design and Entrepreneurship Alliance (IDEA) Funding of BME- Innovation, Design and Entrepreneurship Alliance (IDEA) BME-IDEA Meeting (PI: Paul Yock) BME-IDEA Meeting (PI: Paul Yock) BME-IDEA Contest (PI: Phil Weilerstein) BME-IDEA Contest (PI: Phil Weilerstein)

NSF Engineering Research Centers (ERCs) with Products in Clinical Use BioEngineering Cluster l MIT - - Bioprocess Engineering, 1985 and 1995 (graduating in 05) l Georgia Tech with Emory University School of Medicine- - Engineering of Living Tissue, 1998 l Johns Hopkins with CMU and MIT, Brigham Women’s Hospital and Johns Hopkins University Hospital - - Computer Integrated Surgical Systems, 1998 l Vanderbilt University with Harvard-MIT, Northwestern Univ. and U. of Texas-Austin - - VaNTH ERC for Bioengineering Educational Technologies, 1999 l U. of Southern California with Caltech and UC-Santa Cruz – Biomimetic Microelectronic Systems, 2003 l U. of Michigan with Mich. St., & Mich. Technological Univ. - - Wireless Integrated Microsytems, 2000 l Northeastern U. with Boston U., U. of Puerto Rico-Mayaguez (UPRM), & Rensselaer - - Subsurface Sensing & Imaging Systems, 2000 l Caltech - - Neuromorphic Systems, 1995, (graduating in 05)

Other Funding Opportunities for Innovation in Bioengineering at NSF Science and Technology Centers (STCs) Science and Technology Centers (STCs) - Office of Integrative Activities Integrative Graduate Education and Research Training (IGERT) Initiatives Integrative Graduate Education and Research Training (IGERT) Initiatives - Div Graduate Education (Directorate Education & Human Resources) Combined Research-Curriculum Development & Educational Innovation Program (CRCD) Combined Research-Curriculum Development & Educational Innovation Program (CRCD) - Div Experimental & Integrative Activities (Directorate for Computer & Information Science and Engineering) Priority Areas Priority Areas Interagency Programs Interagency Programs

Role of Interagency Efforts in Fostering Bioengineering Innovation Interagency Activity Groups for Bioengineering Interagency Activity Groups for Bioengineering Interagency Working Groups for Bioengineering Interagency Working Groups for Bioengineering Interagency Funding Programs for Bioengineering Interagency Funding Programs for Bioengineering

Interagency Activity Groups and Working Groups for Bioengineering The DHHS Medical Technology Innovation Task Force The DHHS Medical Technology Innovation Task Force Image Guided Interventions (IGI) Committee Image Guided Interventions (IGI) Committee NSF Scholar in Residence at FDA Program NSF Scholar in Residence at FDA Program NIH/NCI Network for Translational Research in Optical Imaging (NTROI) NIH/NCI Network for Translational Research in Optical Imaging (NTROI) Interagency Modeling and Analysis Group (IMAG) Interagency Modeling and Analysis Group (IMAG) NIH Biomaterials and Medical Implant Science (BMIS) Committee NIH Biomaterials and Medical Implant Science (BMIS) Committee Multi-Agency Tissue Engineering and Sciences (MATES) Group Multi-Agency Tissue Engineering and Sciences (MATES) Group Working Group on the Interface of the Life Sciences and Physical Sciences Working Group on the Interface of the Life Sciences and Physical Sciences Biomass Research and Development Board Biomass Research and Development Board

INTERAGENCY PROGRAMS FOR BIOENGINEERING Collaborative Research in Computational Neuroscience (NSF/NIH) Collaborative Research in Computational Neuroscience (NSF/NIH) NIH-NSF Bioengineering and Bioinformatics Summer Institutes (BBSI) NIH-NSF Bioengineering and Bioinformatics Summer Institutes (BBSI) Quantitative Systems Biotechnology (2005 ended) Quantitative Systems Biotechnology (2005 ended)

INTERAGENCY PROGRAMS FOR BIOENGINEERING (Cont’d) Joint DMS/BIO/NIGMS Initiative to Support Research in the Area of Mathematical Biology Joint DMS/BIO/NIGMS Initiative to Support Research in the Area of Mathematical Biology DDDAS: Dynamic Data Driven Applications Systems DDDAS: Dynamic Data Driven Applications Systems Interagency Opportunities in Multi-Scale Modeling in Biomedical, Biological, and Behavioral Systems Interagency Opportunities in Multi-Scale Modeling in Biomedical, Biological, and Behavioral Systems (NSF, NIH, NASA, DOE) (NSF, NIH, NASA, DOE)

Concluding Remarks Innovation in Bioengineering Innovation in Bioengineering Novel ideas Novel ideas –“Integrative” approaches; complex/open-ended problems Innovation leading to products and clinical use Innovation leading to products and clinical use –Better health care delivery; economic growth Integration of research and education for innovation Integration of research and education for innovation –All innovations come from education –“Real world experiences”; teaching innovation and entrepreneurship NSF Programs Fostering Innovation in Bioengineering NSF Programs Fostering Innovation in Bioengineering - BME/RAPD, SGER, ERC, SBIR, STTR, GOALI, STC, IGERT, CRCD Future: Collaborations Future: Collaborations - Interagency Activity and Working Groups for Bioengineering - Interagency Funding Programs

Thanks for the invitation!