United States Department of Agriculture Food Safety and Inspection Service FSIS Risk Assessments for E. coli O157:H7 Dr. Carl Schroeder Office of Public.

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United States Department of Agriculture Food Safety and Inspection Service FSIS Risk Assessments for E. coli O157:H7 Dr. Carl Schroeder Office of Public Health Science Risk Assessment and Residue Division April 9, 2008

United States Department of Agriculture Food Safety and Inspection Service Risk Assessment Process Develop a plan and gather data Formulate questions Develop risk assessment model Peer review Public presentation Update based on comments Post to web

United States Department of Agriculture Food Safety and Inspection Service

Questions What is the risk of illness from E. coli O157:H7 in ground beef? What is the occurrence and extent of E. coli O157:H7 contamination at points along the farm- to-table continuum?

United States Department of Agriculture Food Safety and Inspection Service Model

United States Department of Agriculture Food Safety and Inspection Service Results Risk of illness –June to September: 1 in every 600,000 ground beef servings –October to May: 1 in every 1.6 million ground beef servings Risk factors for contamination –Prevalence of E. coli at feedlots –Occurrence and extent of carcass contamination –Effectiveness of procedures used to decontaminate carcasses –Effect of carcass chilling

United States Department of Agriculture Food Safety and Inspection Service Conclusion Mitigations during cattle production and slaughter are effective for reducing the risk of illness from E. coli O157:H7 in ground beef

United States Department of Agriculture Food Safety and Inspection Service

Question Do non-intact blade-tenderized beef steaks pose a greater risk to the consumer from E. coli O157:H7 compared to intact beef steaks?

United States Department of Agriculture Food Safety and Inspection Service Model

United States Department of Agriculture Food Safety and Inspection Service Results Contamination with E. coli O157:H7 –2.6 per 10 million servings for intact –3.7 per 10 million servings for non-intact Risk of illness –1 illness per 15.9 million servings for intact –1 illness per 14.2 million servings for non-intact

United States Department of Agriculture Food Safety and Inspection Service Conclusion The risk of illness from E. coli O157:H7 in non- intact beef steaks is not significantly higher than intact beef steaks

United States Department of Agriculture Food Safety and Inspection Service E. coli O157:H7 Pre-harvest Risk Assessment

United States Department of Agriculture Food Safety and Inspection Service Objectives Develop a screening tool to allow more rapid assessment of pre-harvest risk management options Determine if pre-harvest intervention is a cost effective food safety strategy under most optimistic assumptions

United States Department of Agriculture Food Safety and Inspection Service Proposed Model CBA A,B,C

United States Department of Agriculture Food Safety and Inspection Service Estimated Completion Fall 2008

United States Department of Agriculture Food Safety and Inspection Service Updated Comparative Risk Assessment for E. coli O157:H7 Intact and Non-intact Beef

United States Department of Agriculture Food Safety and Inspection Service Objectives Estimate the risk of illness from E. coli O157:H7 in non-intact vs. intact beef steaks

United States Department of Agriculture Food Safety and Inspection Service Proposed Model Updated 2002 model to include data for –Translocation and distribution of E. coli O157:H7 in beef from mechanical and chemical tenderization –Growth of E. coli O157:H7 in non-intact at various temperatures –Effect of cooking on E. coli O157:H7 in non-intact steaks –Effect of sanitation on removal of E. coli O157:H7 from blades/needles used to tenderize beef

United States Department of Agriculture Food Safety and Inspection Service Estimated Completion Fall 2009

United States Department of Agriculture Food Safety and Inspection Service Summary FSIS is conducting a risk assessment on pre- harvest interventions for reducing E. coli O157:H7 in beef FSIS plans to update its comparative risk assessment for E. coli O157:H7 in intact and non-intact beef All FSIS risk assessments available on the web: