Reference Information Unless otherwise noted, all mass spectral data was obtained from: National Institute of Standards and Technology (NIST) Standard.

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Presentation transcript:

Reference Information Unless otherwise noted, all mass spectral data was obtained from: National Institute of Standards and Technology (NIST) Standard Reference Database at webbook.nist.gov/chemistry/ Slide 16 image: Integrated Spectral Data Base System for Organic Compounds at Webspectra at The picture on slide 4 was obtained from:

Analytical Chemistry Chromatography (Separations) Mass Spectrometry Infrared (IR) Spectroscopy Nuclear Magnetic Resonance (NMR) Spectroscopy X-ray Crystallography (visual solid state molecular structure)

Mass Spectrometry What insights are we hoping to gain? Molecular Mass/Isotopic Distribution Molecular Formula Some Structural Characteristics – Fragmentation Pattern

Only molecules of the correct m/z (mass/charge) will make it to the detector.

EI-MS of 2,2-Dimethyl Pentane

Peaks with smaller m/z values __ called fragment ion peaks __ represent positively charged fragments of the parent molecule

EI-MS of 2,2-Dimethyl Pentane

EI-MS of n-Propanol

EI-MS of 4-Heptanone

Isotopes

EI-MS of Benzyl Bromide

Isotopes

EI-MS of Benzyl Bromide

EI-MS of 4-Chloroanisole

Isotopes

What about Identical Masses?

Exact Mass