Copyright © 2009 Pearson Education, Inc. Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Chapter 10.

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Presentation transcript:

Copyright © 2009 Pearson Education, Inc. Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Chapter 10 DNA Structure and Analysis Copyright © 2009 Pearson Education, Inc.

10.1The Genetic Material Must Exhibit Four Characteristics Replication Storage of information Expression of information Variation by mutation

Copyright © 2009 Pearson Education, Inc. Figure 10.1

Copyright © 2009 Pearson Education, Inc. 10.2Until 1944, Observations Favored Protein as the Genetic Material

Copyright © 2009 Pearson Education, Inc. Figure 10.2

Copyright © 2009 Pearson Education, Inc. 10.3Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages Transformation: Early Studies

Copyright © 2009 Pearson Education, Inc. Figure 10.3

Copyright © 2009 Pearson Education, Inc. Table 10.1

Copyright © 2009 Pearson Education, Inc. 10.3Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages Transformation: The Avery, MacLeod, and McCarty Experiment

Copyright © 2009 Pearson Education, Inc. Figure 10.4

Copyright © 2009 Pearson Education, Inc. 10.3Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages The Hershey–Chase Experiment

Copyright © 2009 Pearson Education, Inc. Figure 10.5

Copyright © 2009 Pearson Education, Inc. Figure 10.6

Copyright © 2009 Pearson Education, Inc. 10.3Evidence Favoring DNA as the Genetic Material Was First Obtained during the Study of Bacteria and Bacteriophages Transfection Experiments

Copyright © 2009 Pearson Education, Inc. 10.4Indirect and Direct Evidence Supports the Concept that DNA Is the Genetic Material in Eukaryotes Indirect Evidence: Distribution of DNA Indirect Evidence: Mutagenesis

Copyright © 2009 Pearson Education, Inc. Table 10.2

Copyright © 2009 Pearson Education, Inc. Figure 10.7

Copyright © 2009 Pearson Education, Inc. 10.4Indirect and Direct Evidence Supports the Concept that DNA Is the Genetic Material in Eukaryotes Direct Evidence: Recombinant DNA Studies

Copyright © 2009 Pearson Education, Inc. 10.5RNA Serves as the Genetic Material in Some Viruses

Copyright © 2009 Pearson Education, Inc. 10.6Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure Nucleotides: Building Blocks of Nucleic Acids

Copyright © 2009 Pearson Education, Inc.

Figure 10.9

Copyright © 2009 Pearson Education, Inc. Figure 10.9a

Copyright © 2009 Pearson Education, Inc. Figure 10.9b

Copyright © 2009 Pearson Education, Inc. Figure 10.10

Copyright © 2009 Pearson Education, Inc. 10.6Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure Nucleoside Diphosphates and Triphosphates

Copyright © 2009 Pearson Education, Inc. Figure 10.11

Copyright © 2009 Pearson Education, Inc. 10.6Knowledge of Nucleic Acid Chemistry Is Essential to the Understanding of DNA Structure Polynucleotides

Copyright © 2009 Pearson Education, Inc. Figure 10.12

Copyright © 2009 Pearson Education, Inc. Figure 10.12a

Copyright © 2009 Pearson Education, Inc. Figure 10.12b

Copyright © 2009 Pearson Education, Inc. 10.7The Structure of DNA Holds the Key to Understanding Its Function Base-Composition Studies X-Ray Diffraction Analysis

Copyright © 2009 Pearson Education, Inc. Table 10.3

Copyright © 2009 Pearson Education, Inc. Figure 10.13

Copyright © 2009 Pearson Education, Inc.

10.7The Structure of DNA Holds the Key to Understanding Its Function The Watson–Crick Model

Copyright © 2009 Pearson Education, Inc. Figure 10.14

Copyright © 2009 Pearson Education, Inc. Figure 10.14a

Copyright © 2009 Pearson Education, Inc. Figure 10.14b

Copyright © 2009 Pearson Education, Inc. Figure 10.14c

Copyright © 2009 Pearson Education, Inc. Figure 10.15

Copyright © 2009 Pearson Education, Inc. Figure 10.16

Copyright © 2009 Pearson Education, Inc. 10.8Alternative Forms of DNA Exist

Copyright © 2009 Pearson Education, Inc. Figure 10.17

Copyright © 2009 Pearson Education, Inc. Figure 10.17a

Copyright © 2009 Pearson Education, Inc. Figure 10.17b

Copyright © 2009 Pearson Education, Inc. 10.9The Structure of RNA Is Chemically Similar to DNA, but Single Stranded

Copyright © 2009 Pearson Education, Inc. Table 10.4

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Absorption of Ultraviolet Light (UV) Sedimentation Behavior

Copyright © 2009 Pearson Education, Inc. Figure 10.18

Copyright © 2009 Pearson Education, Inc. Figure 10.19

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Denaturation and Renaturation of Nucleic Acids

Copyright © 2009 Pearson Education, Inc. Figure 10.20

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Molecular Hybridization

Copyright © 2009 Pearson Education, Inc. Figure 10.21

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Fluorescent in situ Hybridization (FISH)

Copyright © 2009 Pearson Education, Inc. Figure 10.22

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Reassociation Kinetics and Repetitive DNA

Copyright © 2009 Pearson Education, Inc. Figure C/C 0 = 1/(1+kC 0 t)

Copyright © 2009 Pearson Education, Inc. Figure 10.24

Copyright © 2009 Pearson Education, Inc. Figure 10.25

Copyright © 2009 Pearson Education, Inc. Figure 10.26

Copyright © 2009 Pearson Education, Inc Many Analytical Techniques Have Been Useful during the Investigation of DNA and RNA Electrophoresis of Nucleic Acids

Copyright © 2009 Pearson Education, Inc. Figure 10.27