Hodgkin’s Lymphoma

Hodgkin’s Lymphoma Disease in which malignant (cancer) cells form in the lymph system Type of cancer that develops in the lymph system –lymph system is part of the body’s immune system

The Lymph System Lymph Lymph vessels Lymph nodes Spleen Thymus Tonsils Bone marrow

Types of Hodgkin’s Lymphoma Nodular sclerosing Mixed cellularity Lymphocyte depletion Lymphocyte-rich Nodular lymphocyte-predominant

Symptoms Painless, swollen lymph nodes in the neck, underarm or groin Unexplained fevers Drenching night sweats Unexplained weight loss Itchy skin Tiredness

Tests/Procedures Physical exam and history Complete blood count Sedimentation rate Blood chemistry studies Lymph node biopsy

Types of Biopsies Excisional biopsy Incisional or core biopsy Needle biopsy or fine needle aspiration Immunophenotyping

Adult Hodgkin’s lymphoma can usually be cured if found and treated early

Staging The process used to find out if cancer cells have spread within the lymph system or to other parts of the body

Staging Process CT scan (CAT scan) PET scan (positron emission tomography scan) Bone marrow biopsy Laparotomy Chest x-ray Thoracentesis

Classification A = patient has no symptoms B = patient has symptoms such as fever, weight loss, or night sweats E = stands for extranodal S = stands for spleen

Stages Stage I A or Stage I B Stage I E Stage II Stage II E Stage III Stage III E Stage III S Stage III E & S Stage IV

Standard Treatment Chemotherapy –systemic –local Radiation therapy –external –internal Surgery

Terms Lymphocytes Reed-Sternberg cells Computed tomography (CT) Computerized axial tomography (CAT) Radionuclide Clinical trial Medical oncologist