CancerCancer. Cancer Cancer is a disease of uncontrolled cell growth. It starts with a single cell that loses its control mechanisms due to a mutation.

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Presentation transcript:

CancerCancer

Cancer Cancer is a disease of uncontrolled cell growth. It starts with a single cell that loses its control mechanisms due to a mutation. That cell starts dividing without limit, and eventually kills the host. The spreading of cancer from one location to another is called metastasis.

Cancer Cancer is the second leading cause of death in the United States. There are many types of cancer, but all cancers start with a single abnormal cell. Abnormal cells multiply quickly. They spread to other parts of the body, invading healthy body tissue and organs. Almost half of all cancer deaths can be prevented with early detection and treatment.

Cancer There are more than 100 types of cancer, including breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma. Cancer symptoms vary widely based on the type of cancer. Cancer treatment includes chemotherapy, radiation, and surgery.

Normal cells vs. Cancer Cells Normal cells are controlled by several factors. –Normal cells stay in the G1 stage of the cell cycle until they are given a specific signal to enter the S phase, in which the DNA replicates and the cell prepares for division. Cancer cells enter the S phase without waiting for a signal. –Normal cells are mortal. This means that they can divide about 50 times and then they lose the ability to divide, and eventually die. This “clock” gets re-set during the formation of the gametes. Cancer cells escape this process of mortality: they are immortal and can divide endlessly –Normal cells that suffer significant chromosome damage destroy themselves due to the action of a gene called p53. Cancer cells either lose or ignore its message and fail to kill themselves.