DNA and Chromosome Structure
A. The Structure of DNA
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base, phosphate group
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base, phosphate group Diphosphates and triphosphates also occur (ATP, GTP)
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base, phosphate group 2. Polymerization occurs by dehydration synthesis OH O-P-O O OH H2OH2O
DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base, phosphate group 2. Polymerization occurs by dehydration synthesis 3. Polmerization results in a nucleic acid with polarity (not same at both ends) 5’ 3’
A purine (A or G) always binds with a pyrimidine (T or C) In fact, A with T (2 h-bonds) And G with C (3 h-bonds) DNA and Chromosome Structure A. The Structure of DNA 1. monomers are “nucleotides” three parts: - pentose sugar, nitrogenous base, phosphate group 2. Polymerization occurs by dehydration synthesis 3. Polmerization results in a nucleic acid with polarity 4. DNA is a double helix – two nucleic acid strands arranged in a complementary, anti-parallel orientation… COMPLEMENTARY…
5’ DNA and Chromosome Structure A. The Structure of DNA 4. DNA is a double helix – two nucleic acid strands arranged in a complementary, anti-parallel orientation… ANTI-PARALLEL…
DNA and Chromosome Structure A. The Structure of DNA 4. DNA is a double helix – two nucleic acid strands arranged in a complementary, anti-parallel orientation…
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes DNA wrapped around histone proteins into nucleosomes
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes DNA wrapped around histone proteins into nucleosomes 6 nucleosomes per solenoid…
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes DNA wrapped around histone proteins into nucleosomes 6 nucleosomes per solenoid… Coiled and supercoiled…
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes DNA wrapped around histone proteins into nucleosomes 6 nucleosomes per solenoid… Coiled and supercoiled… Folded to a metaphase chromosome
DNA and Chromosome Structure A. DNA Structure B. Chromosome Structure 1. Eukaryotic chromosomes DNA wrapped around histone proteins into nucleosomes 6 nucleosomes per solenoid… Coiled and supercoiled… Folded to a metaphase chromosome