Top Five Papers in Transplant ID 2014-2015 Selected using a Completely Unscientific Polling Method Heavily Influenced by Personal Opinion* Not that of.

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Presentation transcript:

Top Five Papers in Transplant ID Selected using a Completely Unscientific Polling Method Heavily Influenced by Personal Opinion* Not that of the presenter, Joanna Schaenman. Shelley Morris just gave me these slides.

Method Requested input from TID 2015 speakers Reviewed “Editor’s Picks” & “Most Cited” papers from – American Journal of Transplantation – Transplantation – Clinical Infectious Diseases – New England Journal of Medicine Personal Opinion

Newsworthy Items for the Past Year in Transplant ID Application of Hepatitis C Virus Treatment to Transplant Candidates/Recipients Management of Transplant Candidates with Multidrug Resistant Organisms New Diagnostic & Treatment Options for Fungal Infections New Living Donor Screening Recommendations New CMV Outcome Information

Exciting News that will Impact the Future of Transplant ID Passage of the HOPE Act in the US and HIV+ transplantation worldwide More new pathogens to worry about – Ebola – Ureaplasma urealyticum

Hepatitis C in Transplant

New Living Donor Screening Guidelines

Desai R. Transplantation 2015;99: UK Transplant Registry data for kidney, liver, heart, lung transplants 10 year post-transplant survival – CMV D-/R- recipients 73.6% significantly higher vs – All other recipients 66.1% (P < ) CMV status was NOT associated with increased risk of cancer Cardiovascular cause of death higher in CMV exposed recipients (18%) vs D-/R- (16%), P = 0.03

Stern, M. Transplantation 2014;98: HR 2.6 HR 1.6 HR 2.2 HR 5.8 A significant risk for graft rejection within 4 weeks after detection of CMV viremia was seen for all organ types Lung>Heart>Liver>Kidney CMV replication and seropositivity continue to play a role in graft rejection even in the modern era of transplantation Swiss Transplant Cohort Study for kidney, liver, heart, lung transplants

Transplantation in the News

HOPE Act signed: November 21, 2013

HIV+ to HIV+ SOT: Preparing for HOPE

Reviewing the HIV+ Recipient Experience

Ebola Outbreak & SOT Kaul D. Amer J Transpl 2015;15:5-6.