Lei Kong, Ph.D. Center for Bioinformatics Peking University ABrowse - A General Purpose Genome Browser Framework.

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Presentation transcript:

Lei Kong, Ph.D. Center for Bioinformatics Peking University ABrowse - A General Purpose Genome Browser Framework

ABrowse Data Visualization User Interface Data Retrieve and Analysis User Space ABrowse Customization

Information Panel Navigation Bar Annotation Canvas GFF Data Expression Data WIG Data BED Data

Display Information in Sub-windows

Multiple Sub Views in One Page

The main canvas can be embedded into html pages of other sites.

ABrowse Data Visualization User Interface Data Retrieve and Analysis User Space ABrowse Customization

A Uniform Query Box for Location and Sequence Searching

Sequence Search

Full Text Search and Complex Query

Compatible with BioMart

Submit data to external bioinformatics platforms

Providing Web Services Interface

ABrowse Data Visualization User Interface Data Retrieve and Analysis User Space ABrowse Customization

ABrowse Provides Track Evaluation Function

Adding/Managing Comments for a Single Entry

More flexible, user may create an instant note by selecting an area on the genome

Uploading User tracks

User May Create/Share Bookmark

ABrowse Data Visualization User Interface Data Retrieve and Analysis User Space ABrowse Customization

Annotation Database Layer Bioinformatic Computational Applications (e.g., Galaxy, Taverna, WebLab) Data Query Web Interface Data Query Web Interface User Interaction Layer Visualization Engine Data Query Engine Data Processing Layer SOAP-based Web Service for Data Retrieval User-Space Engine BioMart Engine Browsing Canvas User-Space Web Interface Genome Browser Web Interface ABrowse Architecture

ABrowse for Site Administrator We provide step by step installation guide. We provide a set of utilities to help site administrators to import data.

ABrowse is Highly Configurable global.abrowse.xml for globle settings genome_name.abrowse.xml for each species, for example: – arabidopsis.abrowse.xml – japonica.abrowse.xml – indica.abrowse.xml

Each single track could have more than one type of view

ABrowse is loosely coupled with DBMS and table schema. Site admin may specify SQL sentence for each track view. – ABrowse demands the tables have 3 columns contains chromosome location including, chr name, chr start and chr end information.

Controlling the Action of Clicking an Entry

ABrowse for Developer By writing rendering classes, developers could add new view types for tracks. ……

Conclusion ABrowse provides an intuitive approach for users to navigate genome interactively. ABrowse supports full text search and bulk data retrieve function. A multiple functional user space is supported by ABrowse. As a framework, ABrowse is easy to install and highly configurable.

Web Access Statistics

RhesusBase CottonDB Rice-Map

Acknowledgement WANG Jun, Ph.D. Student Prof. GAO Ge Prof. LUO Jingchu We appreciate great help from BioMart Galaxy TAIR VISTA

Thanks for Your Attention Comments & Suggestions to