“ Anticancer agents. Drugs overdose and poisoning.” Kharkiv National Medical University Department of Pharmacology and Medical Prescription assistant Gordiychuk.

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Presentation transcript:

“ Anticancer agents. Drugs overdose and poisoning.” Kharkiv National Medical University Department of Pharmacology and Medical Prescription assistant Gordiychuk D.

Drugs overdose and poisoning.

AgentsIndications Activated charcoal with sorbitalused for many oral toxins Atropinemuscarine, organophosphate and carbamate insecticides Calcium chloridecalcium channel blockers, black widow spider bites Calcium gluconatehydrofluoric acid Chelators such as EDTA, dimercaprol (BAL), penicillamine, and 2,3-dimercaptosuccinic acid (DMSA, succimer) heavy metal poisoning Cyanide antidote (amyl nitrite, sodium nitrite, or thiosulfate) cyanide poisoning Deferoxamine mesylateiron poisoning Digoxin Immune Fab antibody (Digibind and Digifab) digoxin poisoning Diphenhydramine hydrochloride and benztropine mesylate extrapyramidal reactions associated with antipsychotic

AgentsIndications Ethanol or fomepizoleethylene glycol poisoning and methanol poisoning Flumazenilbenzodiazepine poisoning Glucagoninsulin coma 100% oxygen or hyperbaric oxygen therapy (HBOT) carbon monoxide poisoning and cyanide poisoning Leucovorinmethotrexate and trimethoprim Methylene bluetreatment of conditions that cause methemoglobinemia Naloxone hydrochlorideopioid poisoning N-acetylcysteineParacetamol (acetaminophen) poisoning Pralidoxime chloride (2-PAM)organophosphate insecticides, followed after atropine Protamine sulfateHeparin poisoning Prussian blueThallium poisoning Physostigmine sulfateanticholinergic poisoning PyridoxineIsoniazid poisoning, ethylene glycol Phytomenadione (vitamin K) and fresh frozen plasma warfarin poisoning and indanedione Sodium bicarbonateDiabetic coma