Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus Brian S. Boxer Wachler, M.D. Lorelei L. Vicente, M.D. BEVERLY.

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Presentation transcript:

Three-Year Study Results of Trans-epithelial Corneal Collagen Crosslinking for Keratoconus Brian S. Boxer Wachler, M.D. Lorelei L. Vicente, M.D. BEVERLY HILLS, CA

Disclosure Financial declaration/conflict of interest: Dr. Boxer Wachler is consultant to Addition Technology and Staar Surgical. Dr. Vicente has no financial interest in the subject matter of this paper.

Purpose To analyze long-term results of patients with keratoconus who had trans-epithelial corneal collagen crosslinking for ectasia.

Methods 7 eyes of 4 patients Mean age: 39 +/- 11 years Trans-epithelial Crosslinking using 0.1 % riboflavin with 0.5% carboxymethylcellulose (RF-CMC) and Tetracaine

Methods Comparison of baseline and follow-up exam of visual parameters after 3 years –UCVA –BCVA –Manifest spherical equivalent (SE) –Refractive cylinder –Topography (NIDEK ARK-9000 OPD- SCAN Refractive Power/Corneal Analyser (Marco, Jacksonville, FL)

Trans-Epithelial Crosslinking Pretreatment with Tetracaine and RF-CMC Instilled one drop after another every 5 minutes for 15 minutes Trans-Epithelial Crosslinking Protocol RF-CMC (q 3 min.) & Tetracaine (q 10 min.) for 30 mins. Applied via soppy, wet surgical sponges (Merocel eye spears, Medtronic, Jacksonville, FL ) Ultraviolet-A light (3.0 mW/cm 2 at 370 nm)

Results

Conclusion Preoperative visual parameters remained stable after Trans-Epithelial Crosslinking with 0.1% riboflavin w/ 0.5% CMC (RF-CMC)