Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February :39 PM

Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome

Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

St. John’s Wort Dietary supplement Antidepressant

Streptokinase Thrombolytic

Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Succinylcholine Paralytic Depolarizing blocker Paralyzes skeletal muscles Bronchoconstrictor

Sucralfate Antiulcer

Sufentanil Opioid General anaesthetic Intravenous anaesthetic

Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor

Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

Sulfasalazine Disease modifying anti-rheumatic drug (DMARD) Metabolized to sulfonamide + salicylate (NSAID) Treatment of IBD

Sulfinpyrazone Uricosuric Anti-gout

Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase

Sulindac NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

Suramin Tropical antiparasitic Treatment of African Trypanosomiasis

Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

Tamoxifen Antineoplastic Antiestrogen Estrogen receptor anatagonist

Tegaserod IBS treatment 5HT 4 receptor agonist

Telmisartan Antihypertensive Angiotensin receptor blocker (ARB)

Temazepam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

Tenecteplase Thrombolytic Tissue plasminogen activator (tPA)

Terazosin Sympatholytic  1 adrenergic antagonist Antihypertensive Treatment for benign prostatic hypertrophy

Terbinafine Allylamine antifungal Inhibits ergosterol synthesis by inhibiting squalene epoxidase

Terbutaline Sympathomimetic  2 adrenergic agonist Short acting bronchodilator Tocolytic Uterine relaxant

Testosterone Androgen Natural male gonadal steroid

Testosterone cypionate Androgen Synthetic depot

Testosterone enanthate Androgen Synthetic depot

Testosterone propionate Androgen Synthetic depot

Tetracaine Local anaesthetic

Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

Thalidomide Antineoplastic Leprosy treatment Anti-angiogenic Anti-TNF 

Theophylline Bronchodilator Methylxanthine Phosphodiesterase inhibitor Used in asthma

Thiabendazole Antihelminthic Treatment of intestinal roundworms

6-Thioguanine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

Thiopental General Anaesthetic Ultra-short-acting barbiturate

Thioridazine Antipsychotic Phenothiazine

Thiotepa Antineoplastic Alkylating agent

Thiothixene Antipsychotic

Thrombopoietin Cytokine Platelet synthesis stimulator

Thromboxane A 2 (TXA 2 ) Autacoid Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

Thyrotropin-releasing Hormone (TRH) Hypothalamic hormone Stimulates release of thyroid stimulating hormone (TSH) from the anterior pituitary

Thyrotropin Thyroid-stimulating Hormone (TSH) Anterior pituitary hormone Stimulates production of thyroxine (T 4 ), triiodothyronine (T 3 ) and thyroglobulin

Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

Ticlopidine Antiplatelet ADP receptor antagonist

Timolol Sympatholytic  adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor

Tissue plasminogen activators Thrombolytics alteplase, reteplase, tenecteplase

Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Tocainide Class I antiarrhythmic Na + channel blocker (activated channels)

Tolbutamide Oral hypoglycemic Sulfonylurea Insulinotropic

Tolterodine Anticholinergic Muscarinic receptor antagonist Prevents urination

Toremifene Estrogen antagonist Selective estrogen receptor modulator (SERM)

Tosemide Loop diuretic Na-K-2Cl symporter inhibitor

Trandopril Antihypertensive Converting enzyme inhibitor

Tranylcypromine Antidepressant Monoamine oxidase inhibitor (MAO-I)

Trastuzumab Antineoplastic Anti-HER2 antibody

Triamcinolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

Triamterene Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

Triazolam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

Trifluoperazine Antipsychotic Phenothiazine

Trifluridine Antiherpes Pyrimidine analog Phosphorylated to inhibitor of viral DNA polymerase

Trihexyphenidyl Antiparkinson Antimuscarinic

Trimethaphan Sympatholytic Anticholinergic Nicotinic antagonist Antihypertensive

Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase

Tripelennamine Classical antihistamine H 1 antagonist

Tubocurarine Paralytic Paralyzes skeletal muscles

Tumor necrosis factor  Cytokine Antineoplastic

Tyramine Indirect sympathomimetic Vasoconstrictor Vasopressor

Ultralente insulin Hormone Insulin analogue Long acting

Urokinase Thrombolytic

Valacyclovir Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase

Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

Valganciclovir Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase

Valproic acid Anticonvulsant

Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

Vancomycin Antibiotic Inhibits cell wall synthesis Not a  lactam

Arginine vasopressin (Antidiuretic hormone; ADH) Hypothalamic (posterior pituitary) hormone Antidiuretic Vasoconstrictor

Vecuronium Paralytic Paralyze skeletal muscles

Verapamil Class IV antiarrhythmic Antihypertensive L-type Ca 2+ channel blocker Antianginal

Vigabatrin Anticonvulsant Irreversible GABA aminotransferase inhibitor

Vinblastine Antineoplastic Vinca alkaloid Natural product

Vincristine Antineoplastic Vinca alkaloid Natural product

Voriconazole Triazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14  demethylase

Warfarin Anticoagulant Vitamin K synthesis inhibitor

Zafirlukast Leukotriene inhibitor LTR 1 and LTD 4 antagonist Asthma treatment

Zalcitabine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Dideoxycytidine (ddC)

Zanamivir Antiviral Inhibits neuraminidase and decreases viral release Treatment of Influenza A & B

Zidovudine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Azidothymidine (AZT)

Zileuton Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma

Zolpidem Sedative/Hypnotic Non-benzodiazepine