The President’s Cancer Panel 2004/2005 Series Translating Research to Reduce the Burden of Cancer Margaret L. Kripke, Ph.D. January 25, 2005

The President’s Cancer Panel National Cancer Act of 1971 Oversees the National Cancer Program Three Members Meet Four Times per Year Reports to the President of the United States

Translating Research to Reduce the Burden of Cancer August 30, 2004–University of California at San Francisco September 27, 2004–The Ohio State University November 1, 2004–M.D. Anderson Cancer Center January 24, 2005–Memorial Sloan- Kettering Cancer Center

Laboratory Clinic Community

Laboratory to Clinic – Barriers Research culture Infrastructure Funding sources Conflict of interest Complexity of clinical trials

Research Culture Differing cultures of physicians and scientists Lack of incentives for team science Creation of knowledge vs. application Departmental structure

Infrastructure Access to human samples Interactive databases Conflict of interest Clinical trials support

Funding Sources Need for “gap” funding Demands on clinicians’ time Need for partnerships

Conflict of Interest/Intellectual Property No universal standards Commercialization Public trust

Complexity of Clinical Trials IRB issues Informed consent Changing regulations HIPAA Trial design

Clinic to Community – Barriers Public trust Communication Community involvement Cost

Where Do We Go From Here? Develop recommendations Deliver Report to President 2005/2006 Series–Focus Groups on Recommendations