Comment on “Chromosomal Instability and Tumors Promoted by DNA Hypomethylation” and “Induction of Tumors in Mice by Genomic Hypomethylation” by Allen S.

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Comment on “Chromosomal Instability and Tumors Promoted by DNA Hypomethylation” and “Induction of Tumors in Mice by Genomic Hypomethylation” by Allen S. Yang, Marcos R.H. Estecio, Guillermo Garcia-Manero, Hagop M. Kantarjian, and Jean-Pierre J. Issa Science Volume 302(5648):1153b-1153b November 14, 2003 Published by AAAS

Fig. 1. Alu and LINE-1 methylation in primary colon tumors and cancer cell lines. Allen S. Yang et al. Science 2003;302:1153b Published by AAAS

Fig. 2. Demethylation of Alu elements by 5-aza-dC in patients with leukemia. Allen S. Yang et al. Science 2003;302:1153b Published by AAAS