The main goal of our project is to explore principles and develop strategies for transforming hydrogen-bonded multilayers into ultrathin highly functional.

Slides:

Advertisements

Similar presentations

Influence of Charge and Network Inhomogeneities on the Swollen-Collapsed Transition in Polyelectrolyte Nanogels Prateek Jha (Northwestern University) Jos.

Advertisements

Porosity Response of Layer-by- Layer Nanocapsules on the Basis of Ultraviolet Light David Huang University of Texas at Austin Department of Biomedical.

Molecularly, collagen exists as a triple helical structure that is stabilized by the presence of the amino acid hydroxyproline. These triple helices further.

Development and Application of a New Method for Epitaxial Growth of Metals, Alloys and Multilayers by Surface Limited Redox Replacement Nikolay Dimitrov,

University of Minho School of Engineering 3B’s Research Group Uma Escola a Reinventar o Futuro – Semana da Escola de Engenharia - 24 a 27 de Outubro de.

Outreach Program: Plastics are all around us. Support: NSF Polymer Program NSF (PI: Chang Ryu)/RPI Polymer Center Student Name: Student Affiliation.

Pathways of Formation of Polymer Coated Lipid-DNA Nanoparticles: Competing Electrostatic Attractions and Polymer Repulsions Cyrus R. Safinya, University.

Stilbene based alternating copolymers exhibit semi-rigid backbones due to the steric crowding of the extra phenyl group (vis-à-vis styrene copolymers)

Our studies on stilbene based alternating copolymers show that the addition of the extra phenyl group (vis-à-vis styrene copolymers) enhances chain stiffness.

Immunomodulatory ultrathin coatings for pancreatic islet transplantation Eugenia Kharlampieva, University of Alabama at Birmingham, DMR Transplantation.

Materials World Network: Design of responsive materials via mixed polymer brush approach Igor Luzinov, Clemson University, DMR The focus of this.

Patterning and Templating on Multi-Layer Films Eric Baer, Case Western Reserve University, DMR Researchers at CWRU are focused on harnessing the.

From personal computers to particle accelerators, High Performance Capacitors are vitally important to the effective functioning of nearly all electronics.

We have demonstrated several successful outcomes to date: (1) Chemical protocols can be readily implemented for the production of elastomeric polypeptides.

CHAPTER1 Materials for Biomedical Applications Biomaterials: Material intended to interface with biological systems to evaluate, treat, augment, or replace.

SURFing the Materials Science and Engineering Laboratory (MSEL) and NIST Center for Neutron Research (NCNR) Robert D. Shull & Terrell A. Vanderah (NIST),

Design of Nanoporous Polymers with New Functional Capabilities Using Monomer Self-Assembly Douglas Gin, University of Colorado at Boulder, DMR

New Polyester Biomaterials: Facile Preparation of Tunable Rapidly Degrading Elastomer Devices Valerie Sheares Ashby, University of North Carolina at Chapel.

Hydrogen-Bonding Assisted Self-Assembly of Lamello- Columnar Phases from Discotic Supermolecules L ei Zhu (University of Connecticut) DMR Hydrogen-bonding.

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Linking chemically dissimilar polymer chains.

CAREER: The Stability and Influence of Metastable Retained Austenite During Fatigue of Advanced Steel Alloys Kip Findley, Colorado School of Mines, DMR.

Atoms  Chemistry is the study of matter. Atoms, Elements, and Compounds- Chapter 6  Atoms are the building blocks of matter. Section 1 Chemistry in.

Charge Photogeneration and Recombination in Organic Semiconductors, Lewis Rothberg, University of Rochester, DMR (with M. Rubner MIT MRSEC, T.

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Figure 1. (a) Synthesis, (b) transmission electron.

This activity presents a comparison study between nanocubes (NC) and nano-octahedra (NO) as well as (100) and (111) thin films of Pt 4 Cu, all used as.

“Bottom-Up” Design of Nanostructured Conducting Polymer Thin Films Evgueni E. Nesterov, Louisiana State University & Agricultural and Mechanical College,

Coherent Carbon Cryogel – Hydride Nanocomposites for Efficient Hydrogen Storage Guozhong Cao, University of Washington, DMR Solid state hydrogen.

Title: Anisotropic Colloidal Magnetic Nanostructures NSF Award Numbers: # Recent years have witnessed a remarkable convergence of physical sciences,

Figure 1. (a) SANS of responsive star PDMAEMA with increasing temperature, the solid lines represent model fitting. (b) Schematic representation of the.

Figure 1. (a) Transmission Electron Micrograph of synthesized FeCo nanoparticles (20nm). (b) X-ray diffraction pattern confirming BCC crystalline structure.

Systematic increase of chain stiffness, via polymer backbone steric crowding from stilbene incorporation, resulted in unique solution and solid state properties.

Chain Dynamics and Layering within Polyelectrolyte Multilayer Films Svelana A. Sukhishvili, Stevens Institute of Technology, DMR Understanding.

“Smart” Adhesion: Controlling Polymer Interfaces with Patterns Alfred J. Crosby, University of Massachusetts, DMR From nano-imprint lithography.

Thrust 1 One thrust of our research is focused on the use of free radical alternating copolymerization to prepare families of precisely charged copolymers.

Chain Dynamics and Layering within Polyelectrolyte Multilayer Films Svetlana A. Sukhishvili, Stevens Institute of Technology, DMR Understanding.

Nanoscale Science and Engineering. Nanoscale Science and Engineering embodies fundamental research and technology development of materials, structures,

The use of polymer layers in light emitting devices has many applications in flexible devices and electronics, and relies on the ability of these polymers.

Self-Assembled Nanoparticle Array for Spintronics and High Frequency Materials DMR PI: Hao Zeng W.L. Shi, Y. Sahoo and Hao Zeng, et al., “Anisotropic.

The main goal of our project is to explore principles and develop strategies for transforming hydrogen-bonded multilayers into ultrathin highly functional.

Younan Xia (NSF Award Number: DMR ) Department of Chemistry, University of Washington Silver nanostructures are containers for surface plasmons.

Ferroelectric Nanolithography Extended to Flexible Substrates Dawn A. Bonnell, University of Pennsylvania, DMR Recent advances in materials synthesis.

LbL MEMS and Protein Structures Annie Cheng Rajesh Kumar Group: Sections: 3.10 and 3.11.

National Science Foundation New Functional Oxides For Electrochemical Energy Storage Ying S. Meng, University of California-San Diego, DMR Outcome:

”Petru Poni” Institute of Macromolecular Chemistry Grigore Ghica Voda Alley No 41 A, Iasi, Romania Project No 254/ Code Project: PNII- RU-TE

BIOLOGY MS. POLLOCK Biochemical Reactions.

Optoelectronic Supramolecular Block-Copolymer Assemblies Aided by Donor- Acceptor Interactions Alexander Sidorenko, University of the Sciences in Philadelphia,

CAREER: An Integrated Research and Education Program for Engineering Functional Block Copolymers Yueh-Lin (Lynn) Loo, University of Texas at Austin, DMR

What is a Liposome? A liposome is a tiny bubble (vesicle), made out of the same material as a cell membrane. Liposomes can be filled with drugs, and used.

Creation and Characterization of Carbon Nanotube Foams and Related Materials Pulickel Ajayan & Ravi Kane, Rensselaer Polytechnic Institute, DMR

Multilayered Anisotropic Microparticles Fabrication of Novel Functional Materials Eric Baer, Case Western Reserve University, DMR Researchers in.

“Smart” Adhesion: Controlling Polymer Interfaces with Patterns Alfred J. Crosby, University of Massachusetts, DMR Nature has shown through examples.

CAREER: Development of Novel Ternary Copolymer Assemblies Robert B. Grubbs, Dartmouth College, DMR Linking chemically dissimilar polymer chains.

CAREER: Shape Responses of Ultrathin Hydrogel Microcapsules Eugemoa Kharlampieva, University of Alabama at Birmingham, DMR Environmental control.

Materials World Network: US-Russia Collaboration on Responsive Micelles at Surfaces – A combined Experimental and Theoretical Approach Svetlana Sukhishvili,

Spin at the Nanoscale: Material Synthesis and Fundamental Physics Min Ouyang, University of Maryland – College Park, DMR In the FY08, we continued.

Materials World Network: US-Russia Collaboration on Responsive Micelles at Surfaces – A Combined Experimental and Theoretical Approach Svetlana A. Sukhishvili,

Co-cross-linked chitosan hydrogel as carrier for the local delivery of cisplatin. Liposome inclusion. Maria José Moura 1,2, Maria Helena Gil 2, Maria Margarida.

The Origin of Cells.

Non-living synthesis of simple organic molecules

NSF MRSEC DMR 2016 University of Pennsylvania - IRG-1:

Preparation of Surface for Biomolecule Immobilization

Non-living synthesis of simple organic molecules

Department of Chemical and Environmental Engineering

NSF NSEC Grant DMR PI: Dr. Richard W. Siegel

Coupled Conformational Equilibria in Peptide-Dendron Conjugates

Materials Computation Center, University of Illinois

Course Overview for Term 5

Department of Chemistry

Photon-Manipulated Drug Release from a Mesoporous Nanocontainer Controlled by Azobenzene-Modiﬁed Nucleic Acid † Molecular Science and Biomedicine Laboratory,

Reversible closslinks

Presentation transcript:

The main goal of our project is to explore principles and develop strategies for transforming hydrogen-bonded multilayers into ultrathin highly functional pH-, temperature- and/or ionic strength-responsive coatings and capsules which reversibly trap and release synthetic macromolecules and proteins. The following findings resulted from our studies: Surface-attached polyacid hydrogels reversibly absorb and release dyes or proteins in response to pH or ionic strength variations. These ultrathin surface hydrogel and can be used as high capacity re-loadable matrices in bioseparation and controlled delivery applications [Langmuir 2007, 23, ]. In the case of hollow capsules with ultrathin wall derived from hydrogen-bonded multilayers, we found that capsules made of a more hydrophobic polycarboxylic acid show minimum of swelling at pH values which are close to physiological [ Soft Matter 2008, 4, ]. Possibility of such tuning has implications for the future application of such capsules for infection control. We have also constructed novel biocompatible polyvinylpyrroli- done/tannic acid (TA) and polyvinylcaprolactam/TA films via layer-by- layer hydrogen-bonding self-assembly. Distinctively, these films are stable up to high pH values of However, their disintegration can be tuned to physiological pH~7.5 by incorporating weak polyacids with low pK a values [Macromolecules 2008, 41, ] The results are important for design of polymer materials with controlled release properties. Responsive Films Derived from Weak Polyelectrolyte Multilayers Svetlana Sukhishvili, Stevens Institute of Technology, DMR pH-controlled dyes or protein absorption and release within/from surface-attached polyacid hydrogels (atop) and capsules (below). 7 μm loading entrapment release pH, I pH 11 pH 9 pH, I Loading Release LbL-derived hydrogels

Education: Funding provided by the NSF supported two graduate students: Veronika Kozlovskaya (5 th -6th year, partial support), Svetlana Pavlukhina (2nd year, partial support). Results were incorporated into graduate courses in the Department of Chemistry and Chemical Biology CH “Polymers at Solid-Liquid Interfaces” and CH/NANO 525 “Techniques of Surface and Nanostructure Characterization”. Knowledge accumulated in the group as a result of the NSF support enabled an undergraduate student, Ms. Kate Santullo, to participate into Spring 2008 and summer 2008 research program. Finally, one high school student, Lessy Pereda, sponsored through the ACS project SEED, is participating this summer in the NSF- supported research in our group. Outreach: Undergraduate and graduate students participate in the summer high school student research programs. The picture shows a high school ACS SEED student Lessy Pereda (front, center) and an undergraduate student Kate Santullo (front, left) working on the NSF project in summer NSF-supported project has been presented in four invited talks given by the PI at International Conferences and symposia during the period of August July Responsive Films Derived from Weak Polyelectrolyte Multilayers Svetlana Sukhishvili, Stevens Institute of Technology, DMR