AP BIOLOGY DNA History & Structure. Nucleic Acid Structure.

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Presentation transcript:

AP BIOLOGY DNA History & Structure

Nucleic Acid Structure

Complimentary Base Pairing

Frederick Griffith

FREDERICK GRIFFITH EXPERIMENT Living S cells (control) Living R cells (control) Heat-killed S cells (control) Mixture of heat-killed S cells and living R cells Mouse dies Living S cells are found in blood sample Mouse healthy Mouse dies RESULTS

Oswald Avery

 Avery and group identified the transforming substance was DNA. His colleagues were McCarty and MacLeod.

Alfred Hershey & Martha Chase

Bacteriophage injecting its DNA into a bacterial cell

Electron Microscope View

Hershey – Chase Experiment

Erwin Chargaff

CHARGAFF’S RULE Adenine = Thymine (DNA) or Uracil (RNA) & Guanine = Cytosine If you know the % composition of 1, you can find the % composition of the other 3.

Rosalind Franklin

DNA from a top view

DNA from a side view

James Watson & Francis Crick with their DNA model

See the HYDROGEN bonds?

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