HAPPY WEDNESDAY In 36 words, compare and contrast mitosis vs meiosis. Use the following words Anaphase Chromosome Cancer Cytokinesis Diploid Gamete.

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HAPPY WEDNESDAY In 36 words, compare and contrast mitosis vs meiosis. Use the following words Anaphase Chromosome Cancer Cytokinesis Diploid Gamete Haploid Meiosis Metaphase Mitosis Prophase Somatic Telophase Tumor

Pg 54 Allele Diploid Metaphase Anaphase Electrophoresis Mitosis Cancer Unit 4 – Cell Cycle Definitions Due Friday (11/6/15) All Parts Due Friday (11/13/15) Period 6 – All Parts Due Thursday (11/12/15) Allele Diploid Metaphase Anaphase Electrophoresis Mitosis Cancer Frameshift Mutation Mutation Cell Cycle Offspring Gamete Centriole Point Mutation Gene Centromere Prophase Genetic Disorder Chromatid Sexual Reproduction Genome Chromosome Haploid Somatic Crossing Over Interphase Telophase Cytokinesis Karyotype Tumor Daughter Cell Meiosis

Collect Today Page 63 – Build a Karyotype (HW Collect Today Page 63 – Build a Karyotype (HW?) Assigned IBB Quiz (Next Week) Notecard ALL PARTS Periods 1-5 (Friday) Periods 6 (TOMORROW) Cell Cycle/Vocabulary Make-Up Quiz (Friday) Most Missed Quiz Make-Up (Friday) Late Notecard Sticker Sheet (-20 points) Page 61 - Mitosis vs Meiosis (-30%) Page 62 – Mitosis Meiosis Summary Modeling (-30%)

What is a Karyotype? Can I produce a model of a karyotype? Essential Question What is a Karyotype? Can I produce a model of a karyotype? Standard B.6H – Describe how techniques such as DNA fingerprinting, genetic modifications, and chromosomal analysis are used to study the genomes of organisms

What each of the human chromosomes look like

Karyotype: A photomicrograph of chromosomes arranged in pairs

In other words… Chromosomes are digitally arranged so that they are matched with their homologue or “partner” chromosome. Homologue chromosomes are the same size, shape, and carry the same genes, and one is inherited from each parent. They are numbered according to size.

Sex determination with karyotype This karyotype has 23 exact pairs, which means the person is female. Note that #23 chromosomes are both X.

Normal human male Note that #23 chromosomes are X and Y.

Is this person female or male?

Trisomy 21 Abnormality shown in karyotype Note that there are three copies of #21 chromosome. This person has Down Syndrome.

Photos of Down Syndrome patients from the National Down Syndrome Society

Correlation between mother’s age and Trisomy 21 incidence

Monosomy X Abnormality shown in karyotype Note this person only has 1 copy of the X chromosome. This female has Turner’s syndrome.

XXY Male (Extra X)

What is a Karyotype? Can I produce a model of a karyotype? Page 63 - Building a Karyotype Essential Question What is a Karyotype? Can I produce a model of a karyotype?