Genomics and Proteomics of HIV and other related human retroviruses Resources –12 members –NIH, DOD, Keck, Snyder funding –Affymetrix, MALDI, LCQ Active collaborations with GWU, NIH, TIGR Output –86 peer reviewed publications –Director of Genomics and Proteomics MS program –Co-Director of the Institute for Proteomics Technology and development Fatah Kashanchi, Ph.D. The George Washington University School of Medicine and Health Sciences
Human Retroviruses Apoptotic HIV (AIDS) Anti-Apoptotic (Cancerous) HTLV-1 (ATL)
Overall approach: Genomics and Proteomics - Standard Microarrays, siRNA, ChIP-Chip - Virus Chip with TIGR - Proteomics and Mass Spec Drug studies and Membrane Proteome - New animal model for HIV using Stem cells (In collaboration with Dr. Saifuddin (Conrad))