2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.1 Statistics for Molecular Biology and Bioinformatics Instructor: Ron S. Kenett

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2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.1 Statistics for Molecular Biology and Bioinformatics Instructor: Ron S. Kenett Course Website: Course textbook: MODERN INDUSTRIAL STATISTICS, Kenett and Zacks, Duxbury Press, 1998

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.2 Course Syllabus Understanding Variability Variability in Several Dimensions Basic Models of Probability Sampling for Estimation of Population Quantities Parametric Statistical Inference Computer Intensive Techniques - Bootstrapping Multivariate Analysis - Multiple Linear Regression Sequential Methods - Statistical Process Control Design of Experiments

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.3 Course Emphasis Interpretation of Statistical tools and methods Reliance on Statistical software (MINITAB) “Learning by doing” Interactive classroom environment Responsibility for the course is shared by: The instructor The students The researchers behind the mini-projects

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.4 Grading Policy A mini-project: 2-3 students per project An exam at the end of the course Final grade split: Difficulty level of final exam will depend on level of efforts put into project

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.5 The mini-project Defined in collaboration with a researcher Has to be completed at the end of the semester Has to be interesting/useful Should provide opportunity to apply one (or more) Statistical tool taught in the course

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.6 The mini-project - 1

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.7 The mini-project - 2

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.8 The mini-project - 3

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.9 The Process of Solving Problems with Statistics The mini-project - 4

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.10 Basic concepts and notation N n Population Sample

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.11 Statistical Inference N n Population Sample DescriptiveStatisticsDescriptiveStatistics ProbabilityProbability

2/23/2016 (c) 2000, Ron S. Kenett, Ph.D.12 Statistical Issues in Life Sciences