Blood transfusions If blood types are not properly matched clumping (agglutination) of the red blood cells can occur. Red blood cells have agglutinins.

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Presentation transcript:

Blood transfusions If blood types are not properly matched clumping (agglutination) of the red blood cells can occur. Red blood cells have agglutinins on their surface (a type of antigen). You blood plasma has antibodies which can react against the agglutinins on your red blood cells

Clotting When platelets in blood are exposed to air chemical reaction occurs. A soluble protein in your plasma changes to an insoluble fibrin – a scab. Vitamin K is important to clotting- made by bacteria in the gut or ingested by eating green veg and cranberries.

Abnormal clotting Haemophilia – slow clotting. High cholesterol and smoking and drinking alcohol increase your chances of clotting Warfarin, aspirin and heparin reduce the bloods ability to clot.

Blood Groups

Rhesus positive and negative Rhesus positive if your plasma has a D – protein. Blood that is Rh-negative can be transfused into a person who is Rh-positive, but an Rh-negative individual can create antibodies for Rh-positive.

Universal Recipient AB+ blood type is referred to as the "universal recipient", Anti-B or Anti-A antibodies in its plasma, and can receive both Rh-positive and Rh-negative blood

Universal Donor O- blood type is called the ‘’universal donor’’ It’s red blood cells have no A or B antigens and are Rh-negative, no other blood type will reject it.

Long Leave Prep Draw a timeline for the discovery and development of blood transfusions. I will take posters in beginning of next term. A4 or A3. Go over everything we have done so far – answer the questions in the book if haven’t already!