NIH: DATA SCIENCE & BD2K Jennie Larkin, PhD Senior Advisor, Extramural Programs and Strategic Planning Office of the Associate Director for Data Science, NIH Health DataPalooza June 1, 2015 DataLab

NIH Big Data to Knowledge Biomedical Data Science Discovery & Innovation BD2K: an investment by all NIH Institutes and Centers catalyze a paradigm shift to ensure that biomedical data and tools can be found, accessed, interoperate, and re- used (FAIR) Goal: use data science to foster an open digital ecosystem (the Commons) that will accelerate efficient, cost-effective biomedical research to enhance health, lengthen life, and reduce illness and disability

The Commons is a shared virtual space where scientists can: Find Deposit Manage Share Reuse data, software, metadata and workflows An environment to find and catalyze the use of shared digital research objects The Commons Concept

The Commons Components Attributes to ensure digital object compliance in the Commons Unique digital object identifiers of some type A minimal set of searchable metadata Physically available in a cloud based Commons provider Clear access rules (especially important for human subjects data) An entry (with metadata) in one or more indices

Data and Tool Resources at NIH NIH has a trove of biomedical and health data and tools NCBI databases PubMed (for biomedical literature) and NIH administrative data (RePORTER) IC-supported data resources (e.g., NIAID’s ImmPort, ADNI, NCI’s Cancer Genomic Cloud, HMP, …) BD2K working to make important data resources “Commons compliant” – FAIR. Search and indexing: Data Discovery Index to help ensure distributed resources can be found Standards: help the community use formats and annotations to ensure resources are well described and can be re-used Interoperate: supporting efforts to get resources more available and interoperable (APIs, etc)

BD2K & the Commons Working with the research community to ensure valuable products of research are more readily available we have the workforce to take advantage of it As more resources come online in the Commons, we anticipate this will catalyze the open digital ecosystem. What would you want and need in the Commons?