Section 5 Infarction Definition: An infarct is an area of ischemic necrosis within a tissue or an organ, produced by occlusion of either its arterial supply.

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Presentation transcript:

Section 5 Infarction Definition: An infarct is an area of ischemic necrosis within a tissue or an organ, produced by occlusion of either its arterial supply or its venous drainage.

Etiology and Pathogenesis Occlusion of a major artery is most often the result of atherosclerosis and its complications (thrombosis, and/or embolism). Rarely, arterial spasm can be severe enough to cause arterial occlusion and infarction.

Classification of infarction (1) White infarcts (anemic infarcts) occur in situations where there is a single blood supply, ① with arterial occlusion, ② in solid tissue with a blood supply that divides in a tree-like configuration.

(Photo is offered by Prof. Orr)

( 参照南京第一医学院病理解剖教研组编 病理组织学图谱, 1961 ,修改 ) )

Classification of infarction (2) Red infarcts (hemorrhagic infarcts) ① With venous occlusion; ② In loose tissues; ③ In tissues with a double circulation; ④ In tissues previously congested.

(Photo is offered by Prof. Orr)